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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Guanine nucleotide exchange factor VAV2
Summary
- UniProt ID
- P52735
- Gene Symbol
-
- VAV2
- Organism
- Homo sapiens (human)
External Links
- PubChem
- P52735
- The Human Metabolome Database
- HMDBP10954
- The O-GlcNAc Database
- P52735
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Angiogenesis
- Guanine-nucleotide releasing factor
- Phosphoprotein
- Reference proteome
- Repeat
- SH2 domain
- SH3 domain
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| cytosol |
| cytoplasm |
| plasma membrane |
| GO Term |
|---|
| metal ion binding |
| phosphotyrosine residue binding |
| guanyl-nucleotide exchange factor activity |
| epidermal growth factor receptor binding |
Sequence
MEQWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISAVSRLSLHSIAQNKGIRPFPSEETTENDDDVYRSLEELADEHDLGEDIYDCVPCEDGGDDIYEDIIKVEVQQPMIRYMQKMGMTEDDKRNCCLLEIQETEAKYYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHSFLRAIDVSVMVGGSTLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYSYELKEIIELLFHKMTDDPMNNKDVKKSHGKMWSYGFYLIHLQGKQGFQFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACKMFLRGTFYQGYMCTKCGVGAHKECLEVIPPCKFTSPADLDASGAGPGPKMVAMQNYHGNPAPPGKPVLTFQTGDVLELLRGDPESPWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERSASRASSRSPASCASYNFSFLSPQGLSFASQGPSAPFWSVFTPRVIGTAVARYNFAARDMRELSLREGDVVRIYSRIGGDQGWWKGETNGRIGWFPSTYVEEEGIQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 116 |
|
|||
| 119 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Azathioprine ADME | Homo sapiens |
| CDC42 GTPase cycle | Homo sapiens |
| DAP12 signaling | Homo sapiens |
| EPH-ephrin mediated repulsion of cells | Homo sapiens |
| FCERI mediated Ca+2 mobilization | Homo sapiens |
| FCERI mediated MAPK activation | Homo sapiens |
| FCGR3A-mediated phagocytosis | Homo sapiens |
| G alpha (12/13) signalling events | Homo sapiens |
| GPVI-mediated activation cascade | Homo sapiens |
| NRAGE signals death through JNK | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
