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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Ligand-gated chloride channel homolog 3
Summary
- Gene Symbol
-
- Lcch3
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- Cell membrane
- Chloride channel
- Disulfide bond
- Glycoprotein
- Ligand-gated ion channel
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q08832 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| chloride transmembrane transport | ||
| ion transmembrane transport | ||
| monoatomic ion transmembrane transport | ||
| regulation of membrane potential | ||
| chemical synaptic transmission |
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| postsynaptic membrane |
|
|
| GABA-A receptor complex | ||
| plasma membrane | ||
| neuron projection |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| neurotransmitter receptor activity | ||
| GABA-A receptor activity | ||
| chloride channel activity | ||
| extracellular ligand-gated monoatomic ion channel activity | ||
| GABA-gated chloride ion channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- gamma-aminobutyric acid receptor subunit beta
- Functional Category
-
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
| Gene Ontology |
|---|
| regulation of membrane potential |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050696 | fetal alcohol spectrum disorder | |
| DOID:0050741 | alcohol dependence | |
| DOID:0060037 | developmental disorder of mental health | |
| DOID:0060041 | autism spectrum disorder | |
| DOID:0080428 | developmental and epileptic encephalopathy 45 | |
| DOID:0080447 | developmental and epileptic encephalopathy 43 | |
| DOID:0080471 | developmental and epileptic encephalopathy 92 | |
| DOID:0111292 | idiopathic generalized epilepsy 10 | |
| DOID:12849 | autistic disorder | |
| DOID:13413 | hepatic encephalopathy |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 117146861 | 7226_0:00351b | |||
| 117186766 | 7229_1:000e1b | |||
| 117575227 | 7291_1:000524 | |||
| 117588800 | 7266_1:002839 | |||
| 117790904 | 198719_1:0033f1 | |||
| 117902066 | 7241_0:001c1f | |||
| 119556565 | 1486046_1:003204 | |||
| 120455576 | 129105_1:003518 | |||
| 122623668 | 7243_1:002f54 | |||
| 128265327 | 103775_0:00341c |
