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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Ligand-gated chloride channel homolog 3
Summary
- Gene Symbol
-
- Lcch3
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- Cell membrane
- Chloride channel
- Disulfide bond
- Glycoprotein
- Ligand-gated ion channel
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q08832 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| chloride transmembrane transport | ||
| ion transmembrane transport | ||
| monoatomic ion transmembrane transport | ||
| regulation of membrane potential | ||
| chemical synaptic transmission |
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| postsynaptic membrane |
|
|
| GABA-A receptor complex | ||
| plasma membrane | ||
| neuron projection |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| neurotransmitter receptor activity | ||
| GABA-A receptor activity | ||
| chloride channel activity | ||
| extracellular ligand-gated monoatomic ion channel activity | ||
| GABA-gated chloride ion channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- gamma-aminobutyric acid receptor subunit beta
- Functional Category
-
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
- X: Mobilome: prophages, transposons
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050696 | fetal alcohol spectrum disorder | |
| DOID:0050741 | alcohol dependence | |
| DOID:0060037 | developmental disorder of mental health | |
| DOID:0060041 | autism spectrum disorder | |
| DOID:0080428 | developmental and epileptic encephalopathy 45 | |
| DOID:0080447 | developmental and epileptic encephalopathy 43 | |
| DOID:0080471 | developmental and epileptic encephalopathy 92 | |
| DOID:0111292 | idiopathic generalized epilepsy 10 | |
| DOID:12849 | autistic disorder | |
| DOID:13413 | hepatic encephalopathy |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 6584324 | 7230_1:000596 | |||
| 6620008 | 7238_1:00347c | |||
| 6631476 | 7244_1:003433 | |||
| 6652923 | 7260_0:003508 | |||
| 6740150 | 7240_1:003480 | |||
| 6899177 | 7237_1:0033fc | |||
| 100124708 | Xenbase:XB-GENE-6030743 | |||
| 100331377 | ZFIN:ZDB-GENE-090313-230 | |||
| 100487991 | Xenbase:XB-GENE-6039478 | |||
| 100488161 | Xenbase:XB-GENE-988598 |
