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heparan sulfate proteoglycan 2
Summary
- Gene Symbol
-
- HSPG2
- Aliases
-
- PRCAN
- endorepellin
- perlecan
- perlecan proteoglycan
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Angiogenesis
- Basement membrane
- Calcium
- Direct protein sequencing
- Disease variant
- Disulfide bond
- EGF-like domain
- Heparan sulfate
- Immunoglobulin domain
- Laminin EGF-like domain
- Metal-binding
- Reference proteome
- Repeat
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P98160 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| animal organ regeneration | ||
| brain development |
|
|
| response to xenobiotic stimulus | ||
| angiogenesis | ||
| positive regulation of endothelial cell proliferation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| Golgi lumen |
|
|
| basement membrane |
|
|
| plasma membrane |
|
|
| focal adhesion |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| collagen V binding |
GO Hierarchy
KEGG BRITE Database
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4489 | malignant epithelial mesothelioma | |
| DOID:450 | myotonic disease | |
| DOID:4624 | Ollier disease | |
| DOID:4626 | hydranencephaly | |
| DOID:4658 | benign mastocytoma | |
| DOID:4659 | extracutaneous mastocytoma | |
| DOID:4676 | uremia | |
| DOID:4766 | embryoma | |
| DOID:4866 | salivary gland adenoid cystic carcinoma | |
| DOID:4905 | pancreatic carcinoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000464 | Abnormality of the neck |
| HP:0000470 | Short neck |
| HP:0000482 | Microcornea |
| HP:0000486 | Strabismus |
| HP:0000490 | Deeply set eye |
| HP:0000504 | Abnormality of vision |
| HP:0000505 | Visual impairment |
| HP:0000508 | Ptosis |
| HP:0000518 | Cataract |
| HP:0000519 | Developmental cataract |
| Disease ID | Disease Name |
|---|---|
| ORPHA:1606 |
|
| ORPHA:800 |
|
| ORPHA:1865 |
|
| OMIM:255800 |
|
| OMIM:224410 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 175126 | WB:WBGene00006787 | ||
| 45320 | FB:FBgn0284408 | ||
| 565429 | ZFIN:ZDB-GENE-080807-4 | DANRE24960 | |
| 100380784 | SALSA43220 | ||
| 115165633 | SALTR88020 | ||
| 103467813 | POERE30093 | ||
| 102290874 | HAPBU05628 | ||
| 113013483 | ASTCA20652 | ||
| 108696836 | Xenbase:XB-GENE-17341349 | ||
| 100494785 | Xenbase:XB-GENE-6465357 |
