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5-hydroxytryptamine receptor 1B
Summary
- Gene Symbol
-
- HTR1B
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Behavior
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Palmitate
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Proteins
Gene Ontology (GO)
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| endoplasmic reticulum | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| Gi/o-coupled serotonin receptor activity | ||
| Gi/o-coupled serotonin receptor activity | ||
| G protein-coupled serotonin receptor activity | ||
| G protein-coupled serotonin receptor activity | ||
| protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- 5-hydroxytryptamine receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| G protein-coupled serotonin receptor signaling pathway |
| chemical synaptic transmission |
| InterPro |
|---|
| 5-hydroxytryptamine receptor family |
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050741 | alcohol dependence | |
| DOID:0050742 | nicotine dependence | |
| DOID:10939 | antisocial personality disorder | |
| DOID:1094 | attention deficit hyperactivity disorder | |
| DOID:12995 | conduct disorder | |
| DOID:14320 | generalized anxiety disorder | |
| DOID:1470 | major depressive disorder | |
| DOID:1574 | alcohol use disorder | |
| DOID:302 | substance abuse |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 3350 | FB:FBgn0263116 | ||
| 3351 | Xenbase:XB-GENE-988006 | ||
| 3352 | FB:FBgn0263116 | ||
| 3354 | FB:FBgn0263116 | ||
| 3355 | WB:WBGene00004779 | ||
| 15550 | FB:FBgn0263116 | ||
| 15551 | Xenbase:XB-GENE-988006 | MOUSE61079 | |
| 15552 | WB:WBGene00004779 | ||
| 15557 | WB:WBGene00004779 | ||
| 24473 | FB:FBgn0263116 |
