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interference hedgehog

Summary

Gene Symbol

ihog

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

33972

PubChem

33972

Alliance of Genome Resources

FB:FBgn0031872

Annotation

Keyword

3D-structure
Disulfide bond
Heparin-binding
Immunoglobulin domain
Proteoglycan
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9VM64

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
smoothened signaling pathway	IDA	17077139
smoothened signaling pathway	IMP	16630821 20501592
smoothened signaling pathway	IGI	16630821 20048000 21044292 25231763
segment specification	IMP	16630821
axon guidance	IBA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

homotypic cell-cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

smoothened signaling pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

imaginal disc pattern formation [inference]

anterior/posterior pattern specification, imaginal disc [inference]

wing disc anterior/posterior pattern formation

wing disc pattern formation

wing disc anterior/posterior pattern formation

anterior/posterior pattern specification [inference]

anterior/posterior pattern specification, imaginal disc [inference]

wing disc anterior/posterior pattern formation

cuticle pattern formation

segment specification

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

sensory organ development [inference]

eye development [inference]

compound eye development

localization [inference]

maintenance of location [inference]

maintenance of protein location [inference]

maintenance of protein location in extracellular region

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

smoothened signaling pathway

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
plasma membrane	IDA	31209108
plasma membrane	IBA
cell surface	IDA	20048000
membrane	IDA	16630821
axon	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cytoneme

neuron projection [inference]

axon

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
patched binding	IPI	20048000
protein binding	IPI	16630821
heparin binding	IDA	17077139
coreceptor activity	IGI	16630821
identical protein binding

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

patched binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

hedgehog family protein binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

molecular transducer activity [inference]

signaling receptor activity [inference]

coreceptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cell adhesion

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 8** entries
InterPro
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin I-set
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
plasma membrane	PMID:31209108
cell surface	PMID:20048000
membrane	PMID:16630821
cytoneme	PMID:23276604 PMID:28825565

Ortholog

Displaying **all 9** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	9543	RGD:1307338
Rattus norvegicus	19289	RGD:1307338
Xenopus tropicalis	33972	Xenbase:XB-GENE-922837
Xenopus tropicalis	50937	Xenbase:XB-GENE-922837
Xenopus tropicalis	50938	Xenbase:XB-GENE-922837
Xenopus tropicalis	57810	Xenbase:XB-GENE-922837
Homo sapiens	91653	HGNC:17173
Homo sapiens	117606	HGNC:17173
Xenopus tropicalis	373711	Xenbase:XB-GENE-922837

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements