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Interference hedgehog

Summary

UniProt ID: Q9VM64
Gene Symbol: ihog CG9211
Gene ID: 33972
Organism: Drosophila melanogaster (fruit fly)

External Links

GlyGen: Q9VM64
PubChem: Q9VM64
Re-Glyco: Q9VM64

Annotation

Keyword: 3D-structure Disulfide bond Heparin-binding Immunoglobulin domain Proteoglycan Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	Reference
smoothened signaling pathway	IDA	PMID
smoothened signaling pathway	IMP	PMID PMID
smoothened signaling pathway	IGI	PMID PMID PMID PMID
segment specification	IMP	PMID
axon guidance	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

homotypic cell-cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

smoothened signaling pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

imaginal disc pattern formation [inference]

anterior/posterior pattern specification, imaginal disc [inference]

wing disc anterior/posterior pattern formation

wing disc pattern formation

wing disc anterior/posterior pattern formation

anterior/posterior pattern specification [inference]

anterior/posterior pattern specification, imaginal disc [inference]

wing disc anterior/posterior pattern formation

cuticle pattern formation

segment specification

developmental process [inference]

anatomical structure development [inference]

animal gross anatomical part developmental process [inference]

animal organ development [inference]

sensory organ development [inference]

eye development [inference]

compound eye development

localization [inference]

maintenance of location [inference]

maintenance of protein location [inference]

maintenance of protein location in extracellular region

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

smoothened signaling pathway

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GO Term	Evidence Code	Reference
plasma membrane	TAS	Reactome
plasma membrane	IDA	PMID
plasma membrane	IBA	GO_REF
cell surface	IDA	PMID
membrane	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell surface

membrane

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

cytoneme

neuron projection [inference]

axon

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GO Term	Evidence Code	Reference
patched binding	IPI	PMID
heparin binding	IDA	PMID
coreceptor activity	IGI	PMID
identical protein binding	IPI	PMID
protein homodimerization activity	IDA	PMID

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

patched binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

hedgehog family protein binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

molecular transducer activity [inference]

signaling receptor activity [inference]

coreceptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MTLLTSSLLLFSLLTSRLEAIPVLEKSPAHPAHSAHPAHPAHPAHPAHPSPGVRILRAPESLVAPLGDEVVLECETSLQPERFEWSHRSSRSPGAGFKYLKTGTAKANVSQEAAISRLRVLVRPDTLGEYRCVGWFGPLVVTSTIARLELASTSLVDAQESESPLQWRVSAGNSVLWSCGQQVQSNPSASWSYYRNGVEIKPEFIGTNGNLFLSNVSSESSGSYSCQATNPASGERIQLPGSLQLQVTPEQRSESKSPHLLRGQPSSQEITIREGSSLLLLCPGVGSPPPTVVWSSPDVVGAVKNKRSKVFGHALEISNTRVNDAGTYICFQDNGVRPALEHYIKVHVEQPPQIVRPPWADLTNEGDRLKLECKATGVPTPEIYWLLNGHSSIDDSEAELSNNFLILHSVLKRHAGYVQCFARNRLGEHSAGTLLQVNPKQIQEPRESGGTHRPKPNQGSRQKQMYPPTPPNVTRLSDESVMLRWMVPRNDGLPIVIFKVQYRMVGKRKNWQTTNDNIPYGKPKWNSELGKSFTASVTDLKPQHTYRFRILAVYSNNDNKESNTSAKFYLQPGAALDPMPVPELLEIEEYSETAVVLHWSLASDADEHLITGYYAYYRPSSSAGEYFKATIEGAHARSFKIAPLETATMYEFKLQSFSAASASEFSALKQGRTQRPKTSTTEEPTLQMGDRDTTTPSHNETFNMSPMLTGTIGGGAVLILLLISTCFCVCRRRNSRSRGNNPNKPRMAELRDDFVPLGNCSPTKQRQRTRHIHITLNPLAQQQQQALEEKNDTDQDAPYYQRPSSYDYDPTLRRMSSSSLRRSQRTLERAGGSNGSNNGNNNNLNQSAEAGSIENPGKPGRVLMKRPRLSSRSENLSSGSLNSVGV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	Source
108	N-linked (GlcNAc...) asparagine	19349973	UniProt GlyGen
215	N-linked (GlcNAc...) asparagine		UniProt GlyGen
472	N-linked (GlcNAc...) asparagine		UniProt GlyGen
563	N-linked (GlcNAc...) asparagine		UniProt GlyGen
699	N-linked (GlcNAc...) asparagine		UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Assembly of the 'signalling complexes'	Drosophila melanogaster
Neurofascin interactions	Drosophila melanogaster
Neutrophil degranulation	Drosophila melanogaster

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

International Collaboration

Acknowledgements