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artemin

Summary

Gene Symbol

Artn

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

362572

PubChem

362572

Alliance of Genome Resources

RGD:621427

Annotation

Keyword

Disulfide bond
Glycoprotein
Growth factor
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q6AYE8
A6JZG2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
axon guidance	ISO
peripheral nervous system development	ISO
peripheral nervous system development	IEP	10719212
peripheral nervous system development	IBA
glial cell-derived neurotrophic factor receptor signaling pathway	ISO

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration [inference]

lymphocyte migration into lymphoid organs

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

glial cell-derived neurotrophic factor receptor signaling pathway

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration [inference]

lymphocyte migration into lymphoid organs

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

developmental process [inference]

anatomical structure morphogenesis [inference]

tissue morphogenesis [inference]

Peyer's patch morphogenesis

anatomical structure development [inference]

system development [inference]

peripheral nervous system development

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

regulation of chemotaxis [inference]

positive regulation of chemotaxis [inference]

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

regulation of positive chemotaxis [inference]

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

regulation of chemotaxis [inference]

positive regulation of chemotaxis [inference]

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

regulation of positive chemotaxis [inference]

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

glial cell-derived neurotrophic factor receptor signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular space	ISO
extracellular space	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
signaling receptor binding	ISO
growth factor activity	ISS
growth factor activity	ISO
growth factor activity	IBA
glial cell-derived neurotrophic factor receptor binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding

receptor tyrosine kinase binding

receptor ligand activity [inference]

growth factor activity

growth factor receptor binding [inference]

glial cell-derived neurotrophic factor receptor binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding [inference]

receptor tyrosine kinase binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

growth factor activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

growth factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

glial cell line-derived neurotrophic factor

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
glial cell-derived neurotrophic factor receptor binding
growth factor activity
peripheral nervous system development
receptor tyrosine kinase binding
system development

Displaying **all 3** entries
InterPro
Cystine-knot cytokine
Glial cell line-derived neurotrophic factor family
Transforming growth factor-beta, C-terminal

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:574	peripheral nervous system disease	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 29 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	9048	HGNC:727	HUMAN49413
Mus musculus	11876	HGNC:727	MOUSE41285
Xenopus tropicalis	362572	Xenbase:XB-GENE-994754
Pan troglodytes	469310		PANTR20868
Bos taurus	530812		BOVIN27118
Macaca mulatta	701641		MACMU21236
Callithrix jacchus	100413091		CALJA41482
Pongo abelii	100460019		PONAB20116
Sus scrofa	100624603		PIGXX30569
Cavia porcellus	100719457		CAVPO24092

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements