integrin subunit beta 3
| UniProt | Protein Name |
|---|---|
| P05106 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of endothelial cell migration | ||
| positive regulation of gene expression | ||
| negative regulation of macrophage derived foam cell differentiation | ||
| positive regulation of fibroblast migration | ||
| negative regulation of lipid storage |
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| nucleoplasm | ||
| plasma membrane | ||
| plasma membrane | ||
| cell-cell junction |
| GO Term | Evidence Code | PMID |
|---|---|---|
| neuregulin binding | ||
| identical protein binding | ||
| vascular endothelial growth factor receptor 2 binding | ||
| vascular endothelial growth factor receptor 2 binding | ||
| metal ion binding |
| Gene Ontology |
|---|
| cell adhesion mediated by integrin |
| cell migration |
| cell-matrix adhesion |
| integrin binding |
| integrin-mediated signaling pathway |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050864 | non-arteritic anterior ischemic optic neuropathy | |
| DOID:0060691 | platelet-type bleeding disorder 16 | |
| DOID:1588 | thrombocytopenia | |
| DOID:2218 | blood platelet disease | |
| DOID:2219 | Glanzmann's thrombasthenia | |
| DOID:2841 | asthma | |
| DOID:5844 | myocardial infarction | |
| DOID:783 | end stage renal disease | |
| DOID:8924 | autoimmune thrombocytopenic purpura | |
| DOID:9119 | acute myeloid leukemia |
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 115617744 | STRHB21261 | ||
| 116435362 | CORMO12604 | ||
| 116839510 | CHEAB11183 | ||
| 117013435 | RHIFE07274 | ||
| 118886865 | BALMU10344 | ||
| 123803040 | URSAM16856 |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025