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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
peptidylglycine alpha-amidating monooxygenase L homeolog
Summary
- Gene Symbol
-
- pam.L
- Organism
- Xenopus laevis (African clawed frog)
Annotation
- Keyword
-
- Alternative splicing
- Calcium
- Copper
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Lyase
- Metal-binding
- Monooxygenase
- Multifunctional enzyme
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| P08478 |
|
| A0A1L8I1N2 |
|
| A0A974E434 |
|
| A0A974I5N1 |
|
| A0A1L8I1N5 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| peptide metabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytoplasmic vesicle | ||
| membrane | ||
| transport vesicle membrane | ||
| extracellular region |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| lyase activity | ||
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen | ||
| metal ion binding | ||
| peptidylamidoglycolate lyase activity | ||
| copper ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- peptidyl-glycine alpha-amidating monooxygenase
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| catalytic activity |
| lyase activity |
| metal ion binding |
| peptide metabolic process |
| peptidylglycine monooxygenase activity |
| InterPro |
|---|
| NHL repeat |
| Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyase |
| Six-bladed beta-propeller, TolB-like |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2526 | prostate adenocarcinoma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 128648701 | 8345_0:000f9e | |||
| 128902291 | 75485_0:003e59 | |||
| 129083931 | 1884717_0:003893 | |||
| 129334290 | 481883_0:002c14 | |||
| 130289587 | 327740_0:000baf | |||
| 130311750 | 327740_0:005426 | |||
| 130476025 | 460621_0:001763 | |||
| 130855164 | 575201_0:00055d | |||
| 131190111 | 499056_0:0012ed | |||
| 131401149 | 77932_0:000276 |
