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UDP glucuronosyltransferase 1 family, polypeptide A2

Summary

Gene Symbol

Ugt1a2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

396527

KEGG Gene ID

rno:396527

PubChem

396527

Alliance of Genome Resources

RGD:1549741

Annotation

Keyword

Endoplasmic reticulum
Glycosyltransferase
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
F7EP24
Q6T5F2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
flavonoid glucuronidation	ISO
response to organic cyclic compound	IEP	11854140
bile acid secretion	ISO
animal organ regeneration	IEP	16222444
liver development	IEP	18938141

GO Hierarchy

biological process

metabolic process [inference]

hormone metabolic process [inference]

estrogen metabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

xenobiotic metabolic process [inference]

xenobiotic glucuronidation

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

estrogen metabolic process

vitamin D metabolic process [inference]

vitamin D3 metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

vitamin D3 metabolic process

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

vitamin metabolic process [inference]

fat-soluble vitamin metabolic process [inference]

vitamin D metabolic process [inference]

vitamin D3 metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

lipid metabolic process [inference]

steroid metabolic process [inference]

estrogen metabolic process

vitamin D metabolic process [inference]

vitamin D3 metabolic process

flavonoid metabolic process [inference]

flavonoid glucuronidation

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

estrogen metabolic process

vitamin D metabolic process [inference]

vitamin D3 metabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

vitamin D3 metabolic process

vitamin D metabolic process [inference]

vitamin D3 metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

xenobiotic metabolic process [inference]

xenobiotic glucuronidation

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

animal organ regeneration

animal organ development [inference]

animal organ regeneration

gland development [inference]

liver development

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to organic cyclic compound

localization [inference]

establishment of localization [inference]

transport [inference]

secretion [inference]

acid secretion [inference]

bile acid secretion

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid secretion

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid secretion

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

estrogen metabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA
endoplasmic reticulum	IBA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 5** entries
GO Term	Evidence Code	PMID
enzyme binding	IBA ISO
protein heterodimerization activity	ISO
retinoic acid binding	ISO
glucuronosyltransferase activity	IEA ISO
protein homodimerization activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

glucuronosyltransferase activity

hexosyltransferase activity [inference]

glucuronosyltransferase activity

binding [inference]

protein binding [inference]

enzyme binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

lipid binding [inference]

isoprenoid binding [inference]

retinoid binding [inference]

retinoic acid binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

retinoic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

retinoic acid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

UDP-glucuronosyltransferase 1-2 isoform X2

Functional Category

C: Energy production and conversion
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
UDP-glycosyltransferase activity
transferase activity

Displaying **all 2** entries
InterPro
UDP-glucuronosyl/UDP-glucosyltransferase
UDP-glycosyltransferase family, conserved site

KEGG BRITE Database

Orthology

K00699

Name

glucuronosyltransferase [EC:2.4.1.17]

References

Rhea

RHEA:21032

glucuronate acceptor + UDP-α-D-glucuronate

acceptor β-D-glucuronoside + H⁺ + UDP

Enzyme

2.4.1.17

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP013549
Gene Name: UDP glucuronosyltransferase 1 family, polypeptide A2

Ortholog

Displaying entries **21 - 30** of **127** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	53508	FB:FBgn0040257
Drosophila melanogaster	53510	FB:FBgn0040259
Drosophila melanogaster	53511	FB:FBgn0040260
Drosophila melanogaster	53512	FB:FBgn0040261
Drosophila melanogaster	53583	FB:FBgn0026754
Drosophila melanogaster	53584	FB:FBgn0026755
Homo sapiens	54575		HUMAN67632
Homo sapiens	54576		HUMAN67631
Homo sapiens	54577		HUMAN67635
Homo sapiens	54600		HUMAN67634

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements