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Standards Ontologies Notations
dual oxidase 2

Summary
Gene Symbol
  • DUOX2
Organism
Sus scrofa (pig)
NCBI Gene
397060
PubChem
397060
Annotation
Keyword
  • Calcium
  • Cell junction
  • Cell membrane
  • Disulfide bond
  • FAD
  • Glycoprotein
  • Hydrogen peroxide
  • Metal-binding
  • NADP
  • Reference proteome
  • Repeat
  • Signal
  • Thyroid hormones biosynthesis
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
Q8HZK2
  • NADH/NADPH thyroid oxidase p138-tox
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 9 in total
GO Term Evidence Code PMID
cuticle development
superoxide anion generation
hydrogen peroxide catabolic process
defense response
response to cAMP
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Dual oxidase
Functional Category
  • P: Inorganic ion transport and metabolism
  • Q: Secondary metabolites biosynthesis, transport and catabolism
  • T: Signal transduction mechanisms
Displaying all 8 entries
Gene Ontology
calcium ion binding
cellular oxidant detoxification
heme binding
metal ion binding
oxidoreductase activity
response to oxidative stress
superoxide anion generation
superoxide-generating NAD(P)H oxidase activity
Displaying entries 1 - 10 of 12 in total
InterPro
EF-Hand 1, calcium-binding site
EF-hand domain pair
EF-hand domain
FAD-binding 8
FAD-binding domain, ferredoxin reductase-type
Ferredoxin-NADP reductase (FNR), nucleotide-binding domain
Ferric reductase transmembrane component-like domain
Ferric reductase, NAD binding domain
Haem peroxidase domain superfamily, animal type
Haem peroxidase superfamily
Ortholog
Displaying entries 31 - 40 of 87 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
101966476 ICTTR12964
102026725 CHILA02516
102131806 MACFA37639
102272102 72004_1:002741
102354060 LATCH13850
102405152 89462_0:0030b6
102431860 MYOLU16465
102461565 PELSI07164
102510795 419612_0:000eeb
102537541 30538_0:004044
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024