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endoglin

Summary

Gene Symbol

ENG

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 397096
PubChem: 397096

Annotation

Keyword

Angiogenesis
Cell adhesion
Cell membrane
Disulfide bond
Glycoprotein
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P37176

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
transforming growth factor beta receptor signaling pathway
regulation of transforming growth factor beta receptor signaling pathway
cell migration
epithelial to mesenchymal transition
cell adhesion

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

cellular developmental process [inference]

cell differentiation [inference]

vasculogenesis

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition

cell motility [inference]

cell migration

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

cellular developmental process [inference]

cell differentiation [inference]

vasculogenesis

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway

regulation of cellular response to growth factor stimulus [inference]

regulation of cellular response to transforming growth factor beta stimulus [inference]

regulation of transforming growth factor beta receptor signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway

Displaying 1 entry
GO Term	Evidence Code	PMID
plasma membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
type II transforming growth factor beta receptor binding
transforming growth factor beta receptor activity
glycosaminoglycan binding
type I transforming growth factor beta receptor binding

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding [inference]

transforming growth factor beta receptor binding [inference]

carbohydrate derivative binding [inference]

glycosaminoglycan binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Transforming growth factor beta receptor type 3

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
cell migration
epithelial to mesenchymal transition
glycosaminoglycan binding
regulation of transforming growth factor beta receptor signaling pathway
transforming growth factor beta binding
transforming growth factor beta receptor activity
transforming growth factor beta receptor signaling pathway
type II transforming growth factor beta receptor binding
vasculogenesis

Displaying 1 entry
InterPro
Zona pellucida domain

Ortholog

Displaying entries **1 - 10** of 64 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	2022		HUMAN98600
Mus musculus	13805		MOUSE34373
Rattus norvegicus	497010		RATNO26852
Canis lupus familiaris	609166		CANLF19420
Bos taurus	615844	9913_0:002223	BOVIN03191
Pan troglodytes	741046		PANTR44904
Monodelphis domestica	100011898		MONDO07334
Pongo abelii	100173392		PONAB36174
Taeniopygia guttata	100226246		TAEGU06418
Callithrix jacchus	100387791		CALJA21090