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chordin, gene 1 S homeolog

Summary

Gene Symbol

chrd.S

Organism

Xenopus laevis (African clawed frog)

External Links

NCBI Gene

398045

PubChem

398045

Alliance of Genome Resources

Xenbase:XB-GENE-865395

Annotation

Keyword

Developmental protein
Glycoprotein
Reference proteome
Repeat
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q91713	Organizer-specific secreted-dorsalizing factor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

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GO Term	Evidence Code	PMID
pattern specification process	IEA
axis specification	IMP	8001117
dorsal/ventral pattern formation
negative regulation of BMP signaling pathway
post-anal tail morphogenesis	IMP	8001117

GO Hierarchy

biological process

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development

pattern specification process

regionalization [inference]

dorsal/ventral pattern formation

axis specification

developmental process [inference]

anatomical structure morphogenesis [inference]

post-anal tail morphogenesis

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development

animal organ development [inference]

kidney development [inference]

pronephros development

system development

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of cellular response to growth factor stimulus [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular region	NAS	8001117
extracellular region	IEA
extracellular space

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	18775317
heparin binding	ISS
BMP binding
syndecan binding	ISS

GO Hierarchy

molecular function

binding [inference]

protein binding

cytokine binding [inference]

BMP binding

proteoglycan binding [inference]

syndecan binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

proteoglycan binding [inference]

syndecan binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

dorsal-ventral patterning protein Sog

Functional Category

G: Carbohydrate transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
BMP binding
dorsal/ventral pattern formation

Displaying **all 2** entries
InterPro
CHRD
VWFC domain

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	8646	Xenbase:XB-GENE-480638
Xenopus tropicalis	12667	Xenbase:XB-GENE-480638
Xenopus tropicalis	32498	Xenbase:XB-GENE-480638
Xenopus tropicalis	398045	Xenbase:XB-GENE-480638