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CD180 molecule

Summary

Gene Symbol

CD180

Organism

Homo sapiens (human)

External Links

NCBI Gene

4064

PubChem

4064

Alliance of Genome Resources

HGNC:6726

Annotation

Keyword

3D-structure
Cell membrane
Direct protein sequencing
Glycoprotein
Inflammatory response
Innate immunity
Leucine-rich repeat
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q99467	Lymphocyte antigen 64 Radioprotective 105 kDa protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
B cell proliferation involved in immune response	IBA
inflammatory response	IEA
lipopolysaccharide-mediated signaling pathway	IEA
positive regulation of lipopolysaccharide-mediated signaling pathway	IGI	10880523
positive regulation of lipopolysaccharide-mediated signaling pathway	IBA

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

immune response [inference]

innate immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

B cell activation [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

B cell proliferation [inference]

B cell proliferation involved in immune response

lymphocyte proliferation [inference]

B cell proliferation [inference]

B cell proliferation involved in immune response

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

B cell activation [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

B cell proliferation [inference]

B cell proliferation involved in immune response

lymphocyte proliferation [inference]

B cell proliferation [inference]

B cell proliferation involved in immune response

signal transduction [inference]

cell surface receptor signaling pathway [inference]

lipopolysaccharide-mediated signaling pathway

cell population proliferation [inference]

leukocyte proliferation [inference]

mononuclear cell proliferation [inference]

lymphocyte proliferation [inference]

B cell proliferation [inference]

B cell proliferation involved in immune response

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

B cell activation [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

B cell proliferation [inference]

B cell proliferation involved in immune response

lymphocyte proliferation [inference]

B cell proliferation [inference]

B cell proliferation involved in immune response

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to other organism [inference]

defense response to other organism [inference]

innate immune response

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to chemical [inference]

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to lipid [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

response to oxygen-containing compound [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of lipopolysaccharide-mediated signaling pathway [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of lipopolysaccharide-mediated signaling pathway [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of lipopolysaccharide-mediated signaling pathway [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of response to external stimulus [inference]

regulation of lipopolysaccharide-mediated signaling pathway [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

lipopolysaccharide-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of lipopolysaccharide-mediated signaling pathway [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
extracellular space	IBA
nucleoplasm	IDA
nucleolus	IDA
plasma membrane	IDA
extracellular matrix	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

external encapsulating structure [inference]

extracellular matrix

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

spindle [inference]

mitotic spindle

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

spindle [inference]

mitotic spindle

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	21857663

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

CD180

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
B cell proliferation involved in immune response
cellular response to lipopolysaccharide
positive regulation of lipopolysaccharide-mediated signaling pathway

Displaying **all 4** entries
InterPro
Cysteine-rich flanking region, C-terminal
Leucine-rich repeat domain superfamily
Leucine-rich repeat, typical subtype
Leucine-rich repeat

Ortholog

Displaying entries **51 - 60** of 79 in total

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Species	Gene ID	Orthologous MAtrix
Myotis lucifugus	102425281	MYOLU00289
Pelodiscus sinensis	102454291	PELSI13323
Erinaceus europaeus	103113907	ERIEU13175
Chlorocebus sabaeus	103222550	CHLSB14096
Carlito syrichta	103258601	CARSF19205
Ursus maritimus	103663622	URSMA04546
Rhinopithecus roxellana	104675618	RHIRO06540
Macaca nemestrina	105475211	MACNE15804
Mandrillus leucophaeus	105539967	MANLE31948
Cercocebus atys	105576614	CERAT43464

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements