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myristoylated alanine rich protein kinase C substrate

Summary

Gene Symbol

MARCKS

Organism

Homo sapiens (human)

External Links

NCBI Gene

4082

PubChem

4082

Alliance of Genome Resources

HGNC:6759

JoGo

MARCKS

TogoVar

MARCKS

Annotation

Keyword

Acetylation
Actin-binding
Calmodulin-binding
Cell membrane
Cytoskeleton
Membrane
Myristate
Phosphoprotein
Proteomics identification
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q6NVI1
P29966	Protein kinase C substrate, 80 kDa protein, light chain

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
apoptotic process	IEA
mitochondrion organization	IEA
actin filament organization	IBA
central nervous system development	IBA
neural tube development	IEA

GO Hierarchy

biological process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization

cellular component assembly [inference]

actin filament bundle assembly

supramolecular fiber organization [inference]

actin filament organization

actin crosslink formation

actin filament bundle organization [inference]

actin filament bundle assembly

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

neural tube development

tube development [inference]

neural tube development

system development [inference]

central nervous system development

cellular developmental process [inference]

cell differentiation [inference]

neurogenesis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

Displaying entries **16 - 17** of 17 in total

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GO Term	Evidence Code	PMID
germinal vesicle	IEA
extracellular exosome	HDA	19056867 20458337

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoplasm

cytoplasm

cell cortex

microtubule organizing center [inference]

centrosome

cytosol

membrane [inference]

plasma membrane

nuclear body [inference]

nuclear speck

cell junction

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

actin filament bundle

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus [inference]

germ cell nucleus [inference]

female germ cell nucleus [inference]

germinal vesicle

endoplasmic reticulum

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus [inference]

germ cell nucleus [inference]

female germ cell nucleus [inference]

germinal vesicle

endoplasmic reticulum

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein kinase C binding	IEA
calmodulin binding	IEA
identical protein binding	IEA
actin filament binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

calmodulin binding

cytoskeletal protein binding [inference]

actin binding [inference]

actin filament binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein kinase C binding

identical protein binding

protein-containing complex binding [inference]

actin filament binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3883	Lynch syndrome	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements