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cadherin 5

Summary

Gene Symbol

CDH5

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 414737
PubChem: 414737

Annotation

Keyword

Calcium
Cell adhesion
Cell junction
Cell membrane
Cleavage on pair of basic residues
Glycoprotein
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B4YYE0	Vascular endothelial cadherin
O02840	Vascular endothelial cadherin

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
cell morphogenesis	IEA	30032202
adherens junction organization	IEA	30032202
cell-cell adhesion mediated by cadherin
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IEA	30032202
cell migration

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion mediated by cadherin

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly

cell-cell junction organization [inference]

multicellular organismal process [inference]

multicellular organism development

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

epithelial cell morphogenesis [inference]

endothelial cell morphogenesis

anatomical structure development [inference]

multicellular organism development

system development [inference]

vasculature development

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of cell killing [inference]

regulation of complement-dependent cytotoxicity

regulation of establishment or maintenance of cell polarity [inference]

regulation of establishment of cell polarity

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
cell junction
plasma membrane	IEA	22301074
adherens junction	IEA	30032202
cell-cell junction
catenin complex	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

catenin complex

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

cell junction

anchoring junction [inference]

cell-cell junction

adherens junction

tight junction [inference]

bicellular tight junction

Displaying **all 4** entries
GO Term	Evidence Code	PMID
beta-catenin binding
protein phosphatase binding
calcium ion binding	IEA	22301074 30032202
cadherin binding	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

beta-catenin binding

enzyme binding [inference]

phosphatase binding [inference]

protein phosphatase binding

cell adhesion molecule binding [inference]

cadherin binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cadherin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 2** entries
Gene Ontology
calcium ion binding
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 3** entries
InterPro
Cadherin conserved site
Cadherin-like superfamily
Cadherin-like

Ortholog

Displaying entries **1 - 10** of 95 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	1003	HUMAN28761
Mus musculus	12562	MOUSE59952
Rattus norvegicus	307618	RATNO14942
Bos taurus	414735	BOVIN10570
Danio rerio	445471	DANRE41097
Pan troglodytes	467991	PANTR12521
Canis lupus familiaris	489775	CANLF16092
Macaca mulatta	693297	MACMU25848
Monodelphis domestica	100018540	MONDO03622
Equus caballus	100065253	HORSE30860