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cadherin 5

Summary

Gene Symbol

CDH5

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 414737
PubChem: 414737

Annotation

Keyword

Calcium
Cell adhesion
Cell junction
Cell membrane
Cleavage on pair of basic residues
Glycoprotein
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B4YYE0	Vascular endothelial cadherin
O02840	Vascular endothelial cadherin

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
cell morphogenesis	IEA	30032202
adherens junction organization	IEA	30032202
cell-cell adhesion mediated by cadherin
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IEA	30032202
cell migration

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion mediated by cadherin

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly

cell-cell junction organization [inference]

multicellular organismal process [inference]

multicellular organism development

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

epithelial cell morphogenesis [inference]

endothelial cell morphogenesis

anatomical structure development [inference]

multicellular organism development

system development [inference]

vasculature development

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of cell killing [inference]

regulation of complement-dependent cytotoxicity

regulation of establishment or maintenance of cell polarity [inference]

regulation of establishment of cell polarity

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
cell junction
plasma membrane	IEA	22301074
adherens junction	IEA	30032202
cell-cell junction
catenin complex	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

catenin complex

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

cell junction

anchoring junction [inference]

cell-cell junction

adherens junction

tight junction [inference]

bicellular tight junction

Displaying **all 4** entries
GO Term	Evidence Code	PMID
beta-catenin binding
protein phosphatase binding
calcium ion binding	IEA	22301074 30032202
cadherin binding	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

beta-catenin binding

enzyme binding [inference]

phosphatase binding [inference]

protein phosphatase binding

cell adhesion molecule binding [inference]

cadherin binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cadherin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 2** entries
Gene Ontology
calcium ion binding
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 3** entries
InterPro
Cadherin conserved site
Cadherin-like superfamily
Cadherin-like

Ortholog

Displaying entries **11 - 20** of 95 in total

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Species	Gene ID	Orthologous MAtrix
Taeniopygia guttata	100222426	TAEGU02801
Callithrix jacchus	100406190	CALJA21399
Ailuropoda melanoleuca	100481085	AILME13557
Meleagris gallopavo	100544769	MELGA03536
Anolis carolinensis	100567792	ANOCA08841
Loxodonta africana	100676069	LOXAF07335
Oreochromis niloticus	100711438	ORENI12947
Cricetulus griseus	100767079	CRIGR06425
Otolemur garnettii	100957369	OTOGA03944
Pan paniscus	100989286	PANPA15352