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MIRAGE
Insulin-like receptor
Summary
- Gene Symbol
-
- InR
- Organism
- Drosophila melanogaster (fruit fly)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Cell membrane
- Cell projection
- Cleavage on pair of basic residues
- Developmental protein
- Differentiation
- Disulfide bond
- Glycoprotein
- Growth regulation
- Manganese
- Metal-binding
- Neurogenesis
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- SH3-binding
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Proteins
| UniProt | Protein Name |
|---|---|
| P09208 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| embryonic development via the syncytial blastoderm | ||
| positive regulation of neuroblast proliferation | ||
| protein phosphorylation | ||
| response to oxidative stress | ||
| transmembrane receptor protein tyrosine kinase signaling pathway |
GO Hierarchy
biological process
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| axon | ||
| growth cone membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein tyrosine kinase activity | ||
| protein tyrosine kinase activity | ||
| transmembrane receptor protein tyrosine kinase activity | ||
| insulin receptor activity | ||
| insulin receptor activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Insulin receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Receptor L-domain |
| Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Tyrosine-protein kinase, active site |
| Tyrosine-protein kinase, catalytic domain |
| Tyrosine-protein kinase, receptor class II, conserved site |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 398006 | HGNC:6091 | ||
| 398022 | Xenbase:XB-GENE-484032 |
