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Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

crumbs

Summary

Gene Symbol

crb

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

42896

KEGG Gene ID

PubChem

42896

Alliance of Genome Resources

FB:FBgn0259685

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Cell projection
Cytoskeleton
Developmental protein
Differentiation
Disulfide bond
EGF-like domain
Glycoprotein
Mitosis
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
P10040	95F
A0A0B4KHS1
A0A0B4K7R8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 63 in total

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GO Term	Evidence Code	PMID
compound eye morphogenesis	IMP
compound eye morphogenesis	IGI
compound eye morphogenesis	IEA
epithelial cell development	IEA
apical constriction	IMP

GO Hierarchy

biological process

cellular process [inference]

establishment or maintenance of cell polarity

maintenance of cell polarity [inference]

maintenance of apical/basal cell polarity

establishment or maintenance of bipolar cell polarity [inference]

establishment or maintenance of apical/basal cell polarity

cell cycle process [inference]

chromosome segregation [inference]

nuclear chromosome segregation

actin filament-based process [inference]

actin cytoskeleton organization [inference]

cortical actin cytoskeleton organization [inference]

assembly of apicomedial cortex actomyosin

actomyosin structure organization [inference]

assembly of apicomedial cortex actomyosin

actin filament-based movement [inference]

actin-mediated cell contraction [inference]

apical constriction

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

cell development [inference]

epithelial cell development

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development [inference]

compound eye photoreceptor development

cell division

microtubule organizing center localization [inference]

centrosome localization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

cortical actin cytoskeleton organization [inference]

assembly of apicomedial cortex actomyosin

actomyosin structure organization [inference]

assembly of apicomedial cortex actomyosin

cortical cytoskeleton organization [inference]

cortical actin cytoskeleton organization [inference]

assembly of apicomedial cortex actomyosin

rhabdomere development

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

adherens junction assembly [inference]

zonula adherens assembly

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

rhabdomere morphogenesis

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

adherens junction assembly [inference]

zonula adherens assembly

cell junction maintenance [inference]

cell-cell junction maintenance [inference]

adherens junction maintenance [inference]

zonula adherens maintenance

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

adherens junction assembly [inference]

zonula adherens assembly

adherens junction organization

adherens junction assembly [inference]

zonula adherens assembly

adherens junction maintenance [inference]

zonula adherens maintenance

cell-cell junction maintenance [inference]

adherens junction maintenance [inference]

zonula adherens maintenance

cellular component maintenance [inference]

cell junction maintenance [inference]

cell-cell junction maintenance [inference]

adherens junction maintenance [inference]

zonula adherens maintenance

membrane organization

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching

pattern specification process [inference]

regionalization [inference]

imaginal disc pattern formation [inference]

dorsal/ventral pattern formation, imaginal disc [inference]

wing disc dorsal/ventral pattern formation

wing disc pattern formation

wing disc dorsal/ventral pattern formation

dorsal/ventral pattern formation [inference]

dorsal/ventral pattern formation, imaginal disc [inference]

wing disc dorsal/ventral pattern formation

photoreceptor cell maintenance

multicellular organismal-level homeostasis

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

amnioserosa maintenance

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis [inference]

cell morphogenesis involved in Malpighian tubule morphogenesis

animal organ morphogenesis [inference]

gland morphogenesis [inference]

salivary gland morphogenesis

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

compound eye morphogenesis

tube morphogenesis

epithelial tube morphogenesis

renal tubule morphogenesis [inference]

Malpighian tubule morphogenesis

embryonic morphogenesis

Malpighian tubule morphogenesis

morphogenesis of embryonic epithelium [inference]

dorsal closure

dorsal closure, amnioserosa morphology change

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of embryonic epithelium [inference]

dorsal closure

epithelial tube morphogenesis

renal tubule morphogenesis [inference]

Malpighian tubule morphogenesis

dorsal closure, amnioserosa morphology change

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

rhabdomere morphogenesis

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching

cell development [inference]

epithelial cell development

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development [inference]

compound eye photoreceptor development

system development [inference]

respiratory system development [inference]

open tracheal system development

animal gross anatomical part developmental process [inference]

embryo development [inference]

embryo development ending in birth or egg hatching

tissue development [inference]

epithelium development [inference]

renal tubule development

tube development [inference]

renal tubule development

animal organ development [inference]

respiratory system development [inference]

open tracheal system development

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

cell development [inference]

epithelial cell development

neuron development [inference]

photoreceptor cell development [inference]

eye photoreceptor cell development [inference]

compound eye photoreceptor development

homeostatic process [inference]

multicellular organismal-level homeostasis

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

amnioserosa maintenance

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

apical protein localization

establishment of localization [inference]

transport [inference]

fluid transport [inference]

epithelial fluid transport [inference]

liquid clearance, open tracheal system

transepithelial transport [inference]

epithelial fluid transport [inference]

liquid clearance, open tracheal system

microtubule organizing center localization [inference]

centrosome localization

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

negative regulation of Notch signaling pathway

positive regulation of signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of intracellular signal transduction [inference]

regulation of hippo signaling [inference]

positive regulation of hippo signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of signaling [inference]

positive regulation of signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of localization [inference]

regulation of protein localization

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport

regulation of transport

regulation of intracellular transport [inference]

regulation of intracellular protein transport

regulation of protein transport [inference]

regulation of intracellular protein transport

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of intracellular protein transport

regulation of growth [inference]

negative regulation of growth [inference]

negative regulation of developmental growth [inference]

negative regulation of organ growth

regulation of developmental growth

regulation of imaginal disc growth

regulation of organ growth [inference]

negative regulation of organ growth

negative regulation of developmental growth [inference]

negative regulation of organ growth

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

negative regulation of growth [inference]

negative regulation of developmental growth [inference]

negative regulation of organ growth

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

negative regulation of developmental process

negative regulation of developmental growth [inference]

negative regulation of organ growth

negative regulation of multicellular organismal process

negative regulation of organ growth

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

negative regulation of Notch signaling pathway

positive regulation of signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of intracellular signal transduction [inference]

regulation of hippo signaling [inference]

positive regulation of hippo signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of developmental process [inference]

regulation of developmental growth

regulation of imaginal disc growth

regulation of organ growth [inference]

negative regulation of organ growth

negative regulation of developmental growth [inference]

negative regulation of organ growth

negative regulation of developmental process

negative regulation of developmental growth [inference]

negative regulation of organ growth

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

negative regulation of Notch signaling pathway

positive regulation of signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of intracellular signal transduction [inference]

regulation of hippo signaling [inference]

positive regulation of hippo signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of cell communication [inference]

positive regulation of signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of macromolecule metabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of primary metabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of proteasomal protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of intracellular protein transport

regulation of multicellular organismal process [inference]

regulation of organ growth [inference]

negative regulation of organ growth

negative regulation of multicellular organismal process

negative regulation of organ growth

regulation of biological quality [inference]

regulation of protein stability [inference]

protein stabilization

Displaying entries **11 - 15** of 19 in total

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GO Term	Evidence Code	PMID
apicolateral plasma membrane	IDA
apicolateral plasma membrane	IPI
photoreceptor connecting cilium	IDA
protein-containing complex	IEA
rhabdomere membrane	IEA

GO Hierarchy

cellular component

protein-containing complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

subapical complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

rhabdomere membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction

apical junction complex

ciliary transition zone [inference]

photoreceptor connecting cilium

cell projection

plasma membrane bounded cell projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein kinase C binding	IPI
Notch binding	IBA
calcium ion binding	IEA
protein binding	IPI
spectrin binding	TAS

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

Notch binding

cytoskeletal protein binding [inference]

spectrin binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein kinase C binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

protein-containing complex binding [inference]

spectrin binding

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying **all 8** entries
Location	References
membrane	FB:FBrf0231198
apical plasma membrane	PMID:10662667 PMID:20498073 PMID:22105348 PMID:22658591 PMID:28306104 PMID:30645584 PMID:32579558
rhabdomere	PMID:19834743 PMID:22105348 PMID:32579558
apicolateral plasma membrane	PMID:11740560 PMID:15302858
photoreceptor connecting cilium	PMID:32579558
cytoplasm	PMID:17923096
nucleus	PMID:26896675
plasma membrane	FB:FBrf0220955 PMID:11076972 PMID:26896675 PMID:28515229

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:10584	retinitis pigmentosa	Alliance of Genome Resources
DOID:14791	Leber congenital amaurosis	Alliance of Genome Resources

Ortholog

Displaying **all 3** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	23418	HGNC:2343
Mus musculus	241324	MGI:2679260
Mus musculus	170788	MGI:2136343

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026