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Guidelines

MIRAGE

DnaJ heat shock protein family (Hsp40) member C10 S homeolog

Summary

Gene Symbol

dnajc10.S

Organism

Xenopus laevis (African clawed frog)

External Links

NCBI Gene

431990

PubChem

431990

Alliance of Genome Resources

Xenbase:XB-GENE-981000

Annotation

Keyword

Disulfide bond
Endoplasmic reticulum
Glycoprotein
Oxidoreductase
Redox-active center
Reference proteome
Repeat
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6NRT6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein folding in endoplasmic reticulum	ISS
protein folding in endoplasmic reticulum	IEA
IRE1-mediated unfolded protein response
ERAD pathway	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

cellular process [inference]

protein folding [inference]

protein folding in endoplasmic reticulum

signal transduction [inference]

endoplasmic reticulum unfolded protein response [inference]

IRE1-mediated unfolded protein response

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response [inference]

IRE1-mediated unfolded protein response

ERAD pathway

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response [inference]

IRE1-mediated unfolded protein response

ERAD pathway

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

ERAD pathway

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

ERAD pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress [inference]

endoplasmic reticulum unfolded protein response [inference]

IRE1-mediated unfolded protein response

ERAD pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response [inference]

IRE1-mediated unfolded protein response

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IEA
endoplasmic reticulum lumen	ISS
endoplasmic reticulum lumen	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein-disulfide reductase activity	ISS
disulfide oxidoreductase activity	IEA
oxidoreductase activity	IEA
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	ISS
misfolded protein binding

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on a sulfur group of donors [inference]

disulfide oxidoreductase activity

protein-disulfide reductase activity

oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor

catalytic activity, acting on a protein [inference]

protein-disulfide reductase activity

binding [inference]

protein binding [inference]

misfolded protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

dnaJ homolog subfamily C member 10

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism

Displaying **all 4** entries
Gene Ontology
IRE1-mediated unfolded protein response
misfolded protein binding
oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
oxidoreductase activity

Displaying **all 5** entries
InterPro
Chaperone J-domain superfamily
DnaJ domain
Thioredoxin domain
Thioredoxin, conserved site
Thioredoxin-like superfamily

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	54431	Xenbase:XB-GENE-980994
Xenopus tropicalis	66861	Xenbase:XB-GENE-980994
Xenopus tropicalis	295690	Xenbase:XB-GENE-980994
Xenopus tropicalis	431990	Xenbase:XB-GENE-980994

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025