MRE11 homolog, double strand break repair nuclease
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of mitotic recombination | ||
| telomere maintenance | ||
| double-strand break repair via homologous recombination | ||
| double-strand break repair via homologous recombination | ||
| DNA double-strand break processing |
| GO Term | Evidence Code | PMID |
|---|---|---|
| site of double-strand break | ||
| site of double-strand break | ||
| BRCA1-C complex | ||
| chromosomal region |
| GO Term | Evidence Code | PMID |
|---|---|---|
| single-stranded DNA endodeoxyribonuclease activity | ||
| single-stranded DNA endodeoxyribonuclease activity | ||
| DNA binding | ||
| DNA helicase activity | ||
| double-stranded DNA binding |
| Gene Ontology |
|---|
| nuclease activity |
| single-stranded DNA endodeoxyribonuclease activity |
| telomere maintenance |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081384 | ataxia-telangiectasia-like disorder-1 | |
| DOID:11054 | urinary bladder cancer | |
| DOID:1380 | endometrial cancer | |
| DOID:1993 | rectum cancer | |
| DOID:219 | colon cancer | |
| DOID:3459 | breast carcinoma | |
| DOID:3883 | Lynch syndrome | |
| DOID:5517 | stomach carcinoma |
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100194879 | SALSA73620 | ||
| 100225368 | TAEGU11605 | ||
| 100356946 | RABIT00709 | ||
| 100411097 | CALJA05187 | ||
| 100447728 | PONAB04188 | ||
| 100483226 | AILME01858 | ||
| 100547823 | MELGA01918 | ||
| 100557944 | ANOCA05220 | ||
| 100594741 | NOMLE09569 | ||
| 100673017 | LOXAF08874 |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025