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acid phosphatase 4 S homeolog

Summary

Gene Symbol

acp4.S

Organism

Xenopus laevis (African clawed frog)

External Links

NCBI Gene

446918

PubChem

446918

Alliance of Genome Resources

Xenbase:XB-GENE-960834

Annotation

Keyword

Disulfide bond
Glycoprotein
Hydrolase
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A8J1LBT9
Q3KQG9	Acid phosphatase 4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
lysosome organization
regulation of neuronal synaptic plasticity
negative regulation of ERBB4 signaling pathway
peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation [inference]

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

lytic vacuole organization [inference]

lysosome organization

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of ERBB4 signaling pathway

regulation of ERBB signaling pathway [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of ERBB4 signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of ERBB4 signaling pathway

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of ERBB4 signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of ERBB4 signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of ERBB4 signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of ERBB4 signaling pathway

regulation of ERBB signaling pathway [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of ERBB4 signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of ERBB4 signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of ERBB4 signaling pathway

regulation of ERBB signaling pathway [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of ERBB4 signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of ERBB4 signaling pathway

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of ERBB signaling pathway [inference]

negative regulation of ERBB4 signaling pathway

regulation of biological quality [inference]

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity

Displaying **all 3** entries
GO Term	Evidence Code	PMID
lysosome
membrane	IEA
postsynaptic membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
acid phosphatase activity	IEA
protein tyrosine phosphatase activity
hydrolase activity	IEA
receptor tyrosine kinase binding

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

acid phosphatase activity

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor tyrosine kinase binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding [inference]

receptor tyrosine kinase binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Phosphatase

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
acid phosphatase activity
dephosphorylation
lysosome organization

Displaying **all 3** entries
InterPro
Histidine acid phosphatase active site
Histidine phosphatase superfamily, clade-2
Histidine phosphatase superfamily

Rhea

RHEA:15017

H₂O + a phosphate monoester

an alcohol + phosphate

Enzyme

PMID

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	93650	Xenbase:XB-GENE-960831
Homo sapiens	176030	HGNC:14376
Homo sapiens	179621	HGNC:14376
Homo sapiens	188683	HGNC:14376
Xenopus tropicalis	446918	Xenbase:XB-GENE-960831