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cytochrome P450 family 19 subfamily A member 1

Summary

Gene Symbol

CYP19A1

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 453433
KEGG Gene ID: ptr:453433
PubChem: 453433

Annotation

Keyword

Heme
Monooxygenase
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A2J8NSX0	CYPXIX Cytochrome P-450AROM Cytochrome P450 19A1 Estrogen synthase
A0A6D2Y496	CYPXIX Cytochrome P-450AROM Cytochrome P450 19A1 Estrogen synthase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
female gonad development	IEA	30032202
response to estradiol	IEA	30032202

GO Hierarchy

biological process

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

female gonad development

developmental process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

female gonad development

anatomical structure development [inference]

animal organ development [inference]

gonad development [inference]

female gonad development

reproductive structure development [inference]

gonad development [inference]

female gonad development

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to organic cyclic compound [inference]

response to estradiol

response to lipid [inference]

response to estradiol

response to oxygen-containing compound [inference]

response to estradiol

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 3** entries
GO Term	Evidence Code	PMID
iron ion binding	IEA	22301074
aromatase activity	IEA	30032202
heme binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [inference]

aromatase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [inference]

aromatase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

heme binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K07434

Name

aromatase [EC:1.14.14.14]

References

2973313

Rhea

RHEA:38195

O₂ + androst-4-ene-3,17-dione

H₂O + H⁺ + formate + estrone

Enzyme

1.14.14.14

PMID

RHEA:38191

O₂ + testosterone

H₂O + H⁺ + formate + 17β-estradiol

Enzyme

1.14.14.14

PMID

Ortholog

Displaying entries **31 - 40** of **108** in total

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Species	Gene ID	Orthologous MAtrix
Macaca mulatta	678697	MACMU42976
Macaca nemestrina	105490390	MACNE03926
Mandrillus leucophaeus	105550746	MANLE28452
Gorilla gorilla gorilla	101137192	GORGO10567
Pan paniscus	100984744	PANPA13355
Pongo abelii	100439777	PONAB08730
Homo sapiens	1588	HUMAN23092
Canis lupus familiaris	494003	CANLF12514
Vulpes vulpes	112920063	VULVU12492
Ailuropoda melanoleuca	100464417	AILME11581

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements