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arachidonate 12-lipoxygenase, 12S type

Summary

Gene Symbol

ALOX12

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 455242
KEGG Gene ID: ptr:455242
PubChem: 455242

Annotation

Keyword

Calcium
Cytoplasm
Dioxygenase
Iron
Lipid metabolism
Metal-binding
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
H2QC17
A0A6D2W8T2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
hepoxilin biosynthetic process	IEA	30032202
arachidonic acid metabolic process	IEA	30032202
lipid oxidation	IEA	30032202
lipoxygenase pathway	IEA	30032202
linoleic acid metabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

linoleic acid metabolic process

hepoxilin metabolic process [inference]

hepoxilin biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

lipoxygenase pathway

unsaturated fatty acid metabolic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

linoleic acid metabolic process

hepoxilin metabolic process [inference]

hepoxilin biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

lipoxygenase pathway

unsaturated fatty acid metabolic process [inference]

lipid modification [inference]

lipid oxidation

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

linoleic acid metabolic process

hepoxilin metabolic process [inference]

hepoxilin biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

lipoxygenase pathway

unsaturated fatty acid metabolic process [inference]

lipid modification [inference]

lipid oxidation

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

linoleic acid metabolic process

hepoxilin metabolic process [inference]

hepoxilin biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

lipoxygenase pathway

unsaturated fatty acid metabolic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

linoleic acid metabolic process

hepoxilin metabolic process [inference]

hepoxilin biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

lipoxygenase pathway

unsaturated fatty acid metabolic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

linoleic acid metabolic process

hepoxilin metabolic process [inference]

hepoxilin biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

lipoxygenase pathway

unsaturated fatty acid metabolic process [inference]

lipid modification [inference]

lipid oxidation

olefinic compound metabolic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

linoleic acid metabolic process

hepoxilin metabolic process [inference]

hepoxilin biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

lipoxygenase pathway

unsaturated fatty acid metabolic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

monocarboxylic acid biosynthetic process [inference]

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

cellular lipid metabolic process [inference]

fatty acid metabolic process [inference]

long-chain fatty acid metabolic process [inference]

arachidonic acid metabolic process

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

linoleic acid metabolic process

hepoxilin metabolic process [inference]

hepoxilin biosynthetic process

fatty acid biosynthetic process [inference]

long-chain fatty acid biosynthetic process [inference]

hepoxilin biosynthetic process

lipoxygenase pathway

unsaturated fatty acid metabolic process [inference]

lipid modification [inference]

lipid oxidation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol	IEA	30032202
sarcolemma	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane [inference]

sarcolemma

Displaying **all 5** entries
GO Term	Evidence Code	PMID
arachidonate 15-lipoxygenase activity	IEA	30032202
linoleate 13S-lipoxygenase activity	IEA	30032202
arachidonate 12(S)-lipoxygenase activity	IEA	30032202
iron ion binding	IEA	22301074
protein binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [inference]

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [inference]

dioxygenase activity [inference]

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [inference]

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00458

Name

arachidonate 12-lipoxygenase [EC:1.13.11.31]

References

Ortholog

Displaying entries **11 - 20** of 63 in total

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Species	Gene ID	Orthologous MAtrix
Ornithorhynchus anatinus	100079469	ORNAN31392
Callithrix jacchus	100400641	CALJA35560
Cercocebus atys	105582822	CERAT17027
Macaca fascicularis	102136652	MACFA12833
Macaca mulatta	713748	MACMU15763
Macaca nemestrina	105473015	MACNE31947
Papio anubis	101012932	PAPAN13859
Homo sapiens	239	HUMAN31209
Canis lupus familiaris	479476	CANLF15421
Ursus americanus	123792172	URSAM23638

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements