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3-hydroxy-3-methylglutaryl-CoA synthase 2

Summary

Gene Symbol

HMGCS2

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 457169
KEGG Gene ID: ptr:457169
PubChem: 457169

Annotation

Keyword

Acetylation
Cholesterol biosynthesis
Mitochondrion
Phosphoprotein
Reference proteome
Transferase
Transit peptide

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A6D2YC48	3-hydroxy-3-methylglutaryl coenzyme A synthase
A0A2J8JUL8	3-hydroxy-3-methylglutaryl coenzyme A synthase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
acetyl-CoA metabolic process	IEA	22301074 30032202
farnesyl diphosphate biosynthetic process, mevalonate pathway	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

amide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

sulfur compound metabolic process [inference]

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

lipid metabolic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

sulfur compound metabolic process [inference]

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying 1 entry
GO Term	Evidence Code	PMID
hydroxymethylglutaryl-CoA synthase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, acyl groups converted into alkyl on transfer [inference]

hydroxymethylglutaryl-CoA synthase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Hominidae

Group Name

hydroxymethylglutaryl-CoA synthase, mitochondrial

Functional Category

H: Coenzyme transport and metabolism
I: Lipid transport and metabolism

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Gene Ontology
acetyl-CoA metabolic process
cholesterol biosynthetic process
cholesterol metabolic process
farnesyl diphosphate biosynthetic process, mevalonate pathway
hydroxymethylglutaryl-CoA synthase activity
identical protein binding
ketone body biosynthetic process
lipid metabolic process
steroid biosynthetic process
steroid metabolic process

Displaying **all 5** entries
InterPro
Hydroxymethylglutaryl-CoA synthase, eukaryotic
Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain
Hydroxymethylglutaryl-coenzyme A synthase, N-terminal
Hydroxymethylglutaryl-coenzyme A synthase, active site
Thiolase-like

KEGG BRITE Database

Orthology

K01641

Name

hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]

References

8566777

Rhea

H₂O + acetoacetyl-CoA + acetyl-CoA

H⁺ + (3S)-hydroxy-3-methylglutaryl-CoA + CoA

Enzyme

2.3.3.10

PMID

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	3158	9606_0:00110b		HUMAN51570
Mus musculus	15360			MOUSE37739
Rattus norvegicus	24450			RATNO23162
Sus scrofa	397673			PIGXX24317
Bos taurus	503684			BOVIN26135
Canis lupus familiaris	607923			CANLF05311
Macaca mulatta	713541			MACMU22547
Equus caballus	100059971			HORSE35197
Ornithorhynchus anatinus	100092884			ORNAN07424
Ciona intestinalis	100175295			CIOIN08080

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Last updated: December 9, 2024