GlyCosmos Portal

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Summary

Gene Symbol

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

45884

KEGG Gene ID

dme:Dmel_CG2666

PubChem

45884

Alliance of Genome Resources

FB:FBgn0001311

Annotation

Keyword

Coiled coil
Glycosyltransferase
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8IPN4
Q9I7P4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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2

3

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GO Term	Evidence Code	PMID
lumen formation, open tracheal system	HMP IMP	21750678 29309404
response to wounding	IEP	19168633
Malpighian tubule morphogenesis	IMP	10502111
chitin biosynthetic process	IMP	25617778
regulation of tube diameter, open tracheal system	IMP	16139230

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

chitin metabolic process [inference]

chitin biosynthetic process

cuticle chitin metabolic process [inference]

cuticle chitin biosynthetic process

cell wall chitin metabolic process [inference]

cell wall chitin biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

amino sugar biosynthetic process [inference]

glucosamine-containing compound biosynthetic process [inference]

chitin biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

chitin metabolic process [inference]

chitin biosynthetic process

cuticle chitin metabolic process [inference]

cuticle chitin biosynthetic process

cell wall chitin metabolic process [inference]

cell wall chitin biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

cell wall macromolecule metabolic process [inference]

cell wall chitin metabolic process [inference]

cell wall chitin biosynthetic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

chitin metabolic process [inference]

chitin biosynthetic process

cuticle chitin metabolic process [inference]

cuticle chitin biosynthetic process

cell wall chitin metabolic process [inference]

cell wall chitin biosynthetic process

amino sugar metabolic process [inference]

amino sugar biosynthetic process [inference]

glucosamine-containing compound biosynthetic process [inference]

chitin biosynthetic process

glucosamine-containing compound metabolic process [inference]

chitin metabolic process [inference]

chitin biosynthetic process

cuticle chitin metabolic process [inference]

cuticle chitin biosynthetic process

cell wall chitin metabolic process [inference]

cell wall chitin biosynthetic process

glucosamine-containing compound biosynthetic process [inference]

chitin biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

amino sugar biosynthetic process [inference]

glucosamine-containing compound biosynthetic process [inference]

chitin biosynthetic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

chitin metabolic process [inference]

chitin biosynthetic process

cuticle chitin metabolic process [inference]

cuticle chitin biosynthetic process

cell wall chitin metabolic process [inference]

cell wall chitin biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

amino sugar biosynthetic process [inference]

glucosamine-containing compound biosynthetic process [inference]

chitin biosynthetic process

organonitrogen compound biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

chitin biosynthetic process

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

trachea morphogenesis

tube morphogenesis [inference]

epithelial tube morphogenesis [inference]

renal tubule morphogenesis [inference]

Malpighian tubule morphogenesis

embryonic morphogenesis [inference]

Malpighian tubule morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

epithelial tube morphogenesis [inference]

renal tubule morphogenesis [inference]

Malpighian tubule morphogenesis

anatomical structure formation involved in morphogenesis [inference]

tube formation [inference]

lumen formation, open tracheal system

epithelial tube formation [inference]

embryonic epithelial tube formation

anatomical structure development [inference]

cuticle development [inference]

chitin-based cuticle development [inference]

chitin-based embryonic cuticle biosynthetic process

system development [inference]

respiratory system development [inference]

open tracheal system development

response to stimulus [inference]

response to stress [inference]

response to wounding

localization [inference]

establishment of localization [inference]

transport [inference]

fluid transport [inference]

epithelial fluid transport [inference]

liquid clearance, open tracheal system

transepithelial transport [inference]

epithelial fluid transport [inference]

liquid clearance, open tracheal system

biological regulation [inference]

regulation of biological quality [inference]

regulation of tube architecture, open tracheal system [inference]

lumen formation, open tracheal system

regulation of tube size, open tracheal system [inference]

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube size, open tracheal system [inference]

regulation of tube diameter [inference]

regulation of tube diameter, open tracheal system

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytoplasm	IDA	25617778
cell periphery	IBA
cell septum	IBA
apical part of cell	IDA	25617778
membrane	ISS	12019232

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
hexosyltransferase activity	IEA
chitin synthase activity	IBA IEA ISS	12019232

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

chitin synthase activity

hexosyltransferase activity

acetylglucosaminyltransferase activity [inference]

chitin synthase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00698

Name

chitin synthase [EC:2.4.1.16]

References

16098962

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R06028	2.4.1.16	G97099AY	G97099AY

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
membrane	FB:FBrf0231198
cytoplasm	PMID:25617778
apical part of cell	PMID:25617778

Rhea

RHEA:16637

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.16

PMID

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	173405	WB:WBGene00000497
Danio rerio	322468	ZFIN:ZDB-GENE-030131-1188
Danio rerio	563138	ZFIN:ZDB-GENE-060503-308
Danio rerio	101886093	ZFIN:ZDB-GENE-060503-226
Saccharomyces cerevisiae S288C	852311	SGD:S000000227