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myosin heavy chain 10

Summary

Gene Symbol

MYH10

Organism

Homo sapiens (human)

External Links

NCBI Gene

4628

PubChem

4628

Alliance of Genome Resources

HGNC:7568

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Actin-binding
Alternative splicing
Calmodulin-binding
Cell adhesion
Cell projection
Cell shape
Coiled coil
Disease variant
Methylation
Myosin
Phosphoprotein
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
G1UI33
P35580	Cellular myosin heavy chain, type B Myosin heavy chain 10 Myosin heavy chain, non-muscle IIb Non-muscle myosin heavy chain B Non-muscle myosin heavy chain IIb

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
mitotic cytokinesis	IDA	15774463
mitotic cytokinesis	IBA
cell adhesion	IEA
regulation of cell shape	IBA
actin filament-based movement	IDA	15845534

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell cycle process [inference]

cytokinesis [inference]

cytoskeleton-dependent cytokinesis [inference]

mitotic cytokinesis

mitotic cell cycle process [inference]

mitotic cytokinesis

actin filament-based process [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization

actin filament-based movement

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

regulation of biological quality [inference]

regulation of cell shape

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
stress fiber	IDA	15774463 7699007
nucleus	HDA	21630459
cytoplasm	IDA	7699007
cytoplasm	IBA
cytosol	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

myosin complex

myosin II complex

cellular anatomical entity [inference]

cytoplasm

cell cortex

membrane [inference]

plasma membrane region [inference]

cleavage furrow

midbody

actin filament bundle [inference]

contractile actin filament bundle [inference]

stress fiber

actomyosin

stress fiber

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton [inference]

postsynaptic actin cytoskeleton

postsynaptic cytoskeleton [inference]

postsynaptic actin cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton [inference]

postsynaptic actin cytoskeleton

postsynaptic cytoskeleton [inference]

postsynaptic actin cytoskeleton

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

myosin filament

myosin II filament

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
microfilament motor activity	IDA	15845534
microfilament motor activity	IMP	24072716
microfilament motor activity	IBA
virus receptor activity	IDA	25428876
actin binding	NAS	7782316

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microfilament motor activity

binding [inference]

protein binding

calmodulin binding

cytoskeletal protein binding [inference]

actin binding

actin filament binding

exogenous protein binding [inference]

virus receptor activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

ADP binding

protein-containing complex binding [inference]

actin filament binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

mRNA binding [inference]

mRNA 5'-UTR binding

RNA stem-loop binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP-dependent activity [inference]

microfilament motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

myosin

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
actin binding
actin filament binding
cytoskeletal motor activity
nucleotide binding

Displaying **all 7** entries
InterPro
IQ motif, EF-hand binding site
Kinesin motor domain superfamily
Myosin S1 fragment, N-terminal
Myosin head, motor domain
Myosin tail
Myosin, N-terminal, SH3-like
P-loop containing nucleoside triphosphate hydrolase

Ortholog

Displaying entries **1 - 10** of 82 in total

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Species	Gene ID	Alliance of Genome Resources
Saccharomyces cerevisiae S288C	4619	SGD:S000001065
Saccharomyces cerevisiae S288C	4625	SGD:S000001065
Saccharomyces cerevisiae S288C	4627	SGD:S000001065
Xenopus tropicalis	4628	Xenbase:XB-GENE-5957388
Saccharomyces cerevisiae S288C	4629	SGD:S000001065
Saccharomyces cerevisiae S288C	8735	SGD:S000001065
Saccharomyces cerevisiae S288C	17879	SGD:S000001065
Saccharomyces cerevisiae S288C	17882	SGD:S000001065
Saccharomyces cerevisiae S288C	17883	SGD:S000001065
Saccharomyces cerevisiae S288C	17884	SGD:S000001065