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neural cell adhesion molecule 1

Summary

Gene Symbol

NCAM1

Aliases

CD56
NCAM

Organism

Homo sapiens (human)

External Links

NCBI Gene

4684

HGNC

7656

KEGG Gene ID

hsa:4684

PubChem

4684

Alliance of Genome Resources

HGNC:7656

Annotation

Keyword

3D-structure
Alternative splicing
Cell adhesion
Cell membrane
Disulfide bond
GPI-anchor
Host cell receptor for virus entry
Host-virus interaction
Immunoglobulin domain
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A087WWD4
P13591

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
epithelial to mesenchymal transition	ISS
viral entry into host cell	IEA
regulation of semaphorin-plexin signaling pathway	ISS
commissural neuron axon guidance	ISS
cell adhesion	IEA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance [inference]

commissural neuron axon guidance

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of semaphorin-plexin signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of semaphorin-plexin signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of semaphorin-plexin signaling pathway

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GO Term	Evidence Code	PMID
cytosol	IDA
extracellular region	IEA
external side of plasma membrane	IDA	17213291
cell surface	IDA	10766765
plasma membrane	IDA TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

side of membrane [inference]

external side of plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
virus receptor activity	IEA
protein binding	IPI	32814053

GO Hierarchy

molecular function

binding [inference]

protein binding

exogenous protein binding [inference]

virus receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000149294

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K06491

Name

neural cell adhesion molecule

References

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0110436	dilated cardiomyopathy 1L	DisGeNET
DOID:0110437	dilated cardiomyopathy 1K	DisGeNET
DOID:0110438	dilated cardiomyopathy 1JJ	DisGeNET
DOID:0110439	dilated cardiomyopathy 1P	DisGeNET
DOID:0110441	dilated cardiomyopathy 2B	DisGeNET
DOID:0110442	dilated cardiomyopathy 1Q	DisGeNET
DOID:0110443	dilated cardiomyopathy 1B	DisGeNET
DOID:0110444	dilated cardiomyopathy 1X	DisGeNET
DOID:0110445	dilated cardiomyopathy 1KK	DisGeNET
DOID:0110446	dilated cardiomyopathy 1W	DisGeNET

Ortholog

Displaying entries **31 - 40** of 76 in total

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Species	Gene ID	Orthologous MAtrix
Canis lupus familiaris	479435	CANLF15281
Vulpes vulpes	112925991	VULVU20166
Ursus americanus	123792576	URSAM00317
Ailuropoda melanoleuca	100471961	AILME04669
Mustela putorius furo	101672003	MUSPF14481
Felis catus	493956	FELCA24216
Panthera leo	122199382	PANLE14855
Tursiops truncatus	101336168	TURTR04716
Balaenoptera musculus	118899980	BALMU08347
Loxodonta africana	100656170	LOXAF01538

GlyTouCan

GlyComb

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UniCarb-DR

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Other Information

Tools

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Summary

External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements