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MIRAGE
nuclear factor kappa B subunit 1
Summary
- Gene Symbol
-
- NFKB1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ANK repeat
- Acetylation
- Activator
- Alternative splicing
- Apoptosis
- Cytoplasm
- DNA-binding
- Direct protein sequencing
- Hydroxylation
- Isopeptide bond
- Lipoprotein
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- S-nitrosylation
- Transcription regulation
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P19838 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of transcription by RNA polymerase II | ||
| regulation of transcription by RNA polymerase II | ||
| transcription by RNA polymerase II | ||
| apoptotic process |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of lipid metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
positive regulation of cellular process [inference]
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- nuclear factor NF-kappa-B
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| Ankyrin repeat-containing domain superfamily |
| Ankyrin repeat |
| Death domain |
| Death-like domain superfamily |
| IPT domain |
| Immunoglobulin E-set |
| Immunoglobulin-like fold |
| NF-kappa-B/Dorsal |
| NFkappaB IPT domain |
| Rel homology dimerisation domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081154 | common variable immunodeficiency 12 | |
| DOID:10283 | prostate cancer | |
| DOID:1612 | breast cancer | |
| DOID:1909 | melanoma | |
| DOID:321 | HTLV-1-associated myelopathy/tropical spastic paraparesis | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:684 | hepatocellular carcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100662194 | LOXAF14195 | ||
| 100730075 | CAVPO16349 | ||
| 100917619 | SARHA17666 | ||
| 100951061 | OTOGA06481 | ||
| 100979341 | PANPA30703 | ||
| 101026781 | PAPAN28112 | ||
| 101035787 | SAIBB15945 | ||
| 101072751 | TAKRU09703 | ||
| 101108228 | SHEEP17192 | ||
| 101153465 | GORGO30439 |
