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sorbitol dehydrogenase

Summary

Gene Symbol

SORD

Organism

Canis lupus familiaris (dog)

External Links

NCBI Gene: 487535
KEGG Gene ID: cfa:487535
PubChem: 487535

Annotation

Keyword

Carbohydrate metabolism
Flagellum
Metal-binding
NAD
Oxidoreductase
Reference proteome
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A8C0NKQ6	L-iditol 2-dehydrogenase Polyol dehydrogenase Xylitol dehydrogenase
A0A8I3QI05	L-iditol 2-dehydrogenase Polyol dehydrogenase Xylitol dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
sorbitol catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

small molecule catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol catabolic process

hexitol catabolic process [inference]

sorbitol catabolic process

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol catabolic process

hexitol catabolic process [inference]

sorbitol catabolic process

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

small molecule catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol catabolic process

hexitol catabolic process [inference]

sorbitol catabolic process

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

hexitol metabolic process [inference]

sorbitol metabolic process [inference]

sorbitol catabolic process

hexitol catabolic process [inference]

sorbitol catabolic process

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

alditol catabolic process [inference]

hexitol catabolic process [inference]

sorbitol catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
zinc ion binding	IEA	22301074
L-iditol 2-dehydrogenase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

L-iditol 2-dehydrogenase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

alcohol dehydrogenase i

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
metal ion binding
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
oxidoreductase activity
zinc ion binding

Displaying **all 6** entries
InterPro
Alcohol dehydrogenase, zinc-type, conserved site
Alcohol dehydrogenase-like, C-terminal
Alcohol dehydrogenase-like, N-terminal
GroES-like superfamily
NAD(P)-binding domain superfamily
Polyketide synthase, enoylreductase domain

KEGG BRITE Database

Orthology

K00008

Name

L-iditol 2-dehydrogenase [EC:1.1.1.14]

References

Rhea

RHEA:20433

xylitol + NAD⁺

H⁺ + D-xylulose + NADH

Enzyme

1.1.1.9

PMID

17216457

RHEA:10160

L-iditol + NAD⁺

keto-L-sorbose + H⁺ + NADH

Enzyme

1.1.1.14

PMID

RHEA:33031

H⁺ + keto-D-fructose + NADH

D-sorbitol + NAD⁺

Enzyme

1.1.1.14

PMID

Ortholog

Displaying entries **1 - 10** of **116** in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	6652	HUMAN22836
Mus musculus	20322	MOUSE32862
Rattus norvegicus	24788	RATNO25772
Pan troglodytes	453394	PANTR10211
Bos taurus	508954	BOVIN01428
Danio rerio	570613	DANRE40437
Macaca mulatta	712784	MACMU40645
Monodelphis domestica	100012620	MONDO05203
Equus caballus	100070575	HORSE16754
Ornithorhynchus anatinus	100087927	ORNAN26540

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements