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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
growth differentiation factor 3
Summary
- Gene Symbol
-
- gdf3
- Organism
- Xenopus tropicalis (tropical clawed frog)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Cytokine
- Developmental protein
- Disulfide bond
- Glycoprotein
- Growth factor
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| Q66KL4 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| anterior/posterior pattern specification | ||
| mesoderm formation | ||
| determination of left/right symmetry |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| morphogen activity | ||
| cytokine activity | ||
| growth factor activity | ||
| protein homodimerization activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Bone morphogenetic protein
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytokine activity |
| growth factor activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050545 | visceral heterotaxy | |
| DOID:0060772 | multiple types of congenital heart defects 6 | |
| DOID:0060838 | isolated microphthalmia 7 | |
| DOID:0060850 | annular pancreas | |
| DOID:0080591 | Klippel-Feil syndrome 3 | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:14323 | Marfan syndrome | |
| DOID:1682 | congenital heart disease | |
| DOID:5082 | liver cirrhosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 2657 | HGNC:4214 | |||
| 9573 | 9606_0:000c64 | HGNC:4218 | ||
| 14559 | MGI:95683 | |||
| 14562 | MGI:95686 | |||
| 30125 | ZFIN:ZDB-GENE-980526-389 | |||
| 179068 | WB:WBGene00000936 | |||
| 306351 | RGD:1304678 | |||
| 394305 | 8355_0:00122f | Xenbase:XB-GENE-865693 | ||
| 396132 | 9031_0:003d72 | |||
| 477702 | 9615_0:0040de |
