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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
growth differentiation factor 3
Summary
- Gene Symbol
-
- gdf3
- Organism
- Xenopus tropicalis (tropical clawed frog)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Cytokine
- Developmental protein
- Disulfide bond
- Glycoprotein
- Growth factor
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| Q66KL4 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| anterior/posterior pattern specification | ||
| mesoderm formation | ||
| determination of left/right symmetry |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| morphogen activity | ||
| cytokine activity | ||
| growth factor activity | ||
| protein homodimerization activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Bone morphogenetic protein
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytokine activity |
| growth factor activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050545 | visceral heterotaxy | |
| DOID:0060772 | multiple types of congenital heart defects 6 | |
| DOID:0060838 | isolated microphthalmia 7 | |
| DOID:0060850 | annular pancreas | |
| DOID:0080591 | Klippel-Feil syndrome 3 | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:14323 | Marfan syndrome | |
| DOID:1682 | congenital heart disease | |
| DOID:5082 | liver cirrhosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 104162997 | 54380_0:002422 | |||
| 104273572 | 57397_0:001b89 | |||
| 104288979 | 50402_0:00259a | |||
| 104300775 | 118200_0:002ea2 | |||
| 104327356 | 30419_0:000fb2 | |||
| 104344298 | 188344_0:001436 | |||
| 104376682 | 121530_0:002049 | |||
| 104386478 | 8897_0:00117c | |||
| 104407938 | 176057_0:002714 | |||
| 104465179 | 240206_0:001efd |
