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Submissions

potassium inwardly-rectifying channel, subfamily J, member 3

Summary

Gene Symbol

Kcnj3

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

50599

PubChem

50599

Alliance of Genome Resources

RGD:2958

Annotation

Keyword

3D-structure
Glycoprotein
Phosphoprotein
Potassium transport
Reference proteome
Transmembrane helix
Voltage-gated channel

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6JF43	Inward rectifier K(+) channel Kir3.1 Potassium channel, inwardly rectifying subfamily J member 3
P63251	Inward rectifier K(+) channel Kir3.1 KGA KGB1 Potassium channel, inwardly rectifying subfamily J member 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
regulation of ion transmembrane transport	IBA
regulation of monoatomic ion transmembrane transport	IBA
response to electrical stimulus	IEP	10215164
potassium ion transmembrane transport	NAS	19703462
potassium ion transmembrane transport	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

response to stimulus [inference]

response to abiotic stimulus [inference]

response to electrical stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport

potassium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion import across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of ion transmembrane transport

regulation of monoatomic ion transport [inference]

regulation of ion transmembrane transport

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

regulation of ion transmembrane transport

regulation of biological quality [inference]

regulation of membrane potential [inference]

regulation of presynaptic membrane potential

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GO Term	Evidence Code	PMID
plasma membrane	IBA
voltage-gated potassium channel complex	ISO
external side of plasma membrane	IDA	11561006
cell surface	IDA	19118198
T-tubule	IDA	11561006

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated potassium channel complex

inward rectifier potassium channel complex [inference]

I(KACh) inward rectifier potassium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

inward rectifier potassium channel complex [inference]

I(KACh) inward rectifier potassium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

inward rectifier potassium channel complex [inference]

I(KACh) inward rectifier potassium channel complex

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic membrane

cell junction [inference]

synapse [inference]

excitatory synapse [inference]

parallel fiber to Purkinje cell synapse

T-tubule

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
inward rectifier potassium channel activity	ISO
inward rectifier potassium channel activity	IDA	9486652
protein binding	IPI	19765080
phosphatidylinositol-4,5-bisphosphate binding	IDA	9486652
G-protein activated inward rectifier potassium channel activity	ISO

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

G-protein activated inward rectifier potassium channel activity

binding [inference]

protein binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

ion binding [inference]

anion binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

inward potassium channel rectifier

Functional Category

G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
inward rectifier potassium channel activity
monoatomic ion transport
regulation of monoatomic ion transmembrane transport

Displaying **all 5** entries
InterPro
Immunoglobulin E-set
Inward rectifier potassium channel, C-terminal
Potassium channel, inwardly rectifying, Kir, cytoplasmic
Potassium channel, inwardly rectifying, Kir
Potassium channel, inwardly rectifying, transmembrane domain

Ortholog

Displaying entries **1 - 10** of 87 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	3760	Xenbase:XB-GENE-1004371	HUMAN65103
Drosophila melanogaster	3762	FB:FBgn0265042
Drosophila melanogaster	3767	FB:FBgn0265042
Drosophila melanogaster	16514	FB:FBgn0265042
Mus musculus	16519	Xenbase:XB-GENE-1004371	MOUSE36239
Xenopus tropicalis	50599	Xenbase:XB-GENE-1004371
Drosophila melanogaster	83535	FB:FBgn0265042
Canis lupus familiaris	488355		CANLF13881
Bos taurus	526088		BOVIN24244
Macaca mulatta	696473		MACMU07092