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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
interleukin 21 receptor
Summary
- Gene Symbol
-
- IL21R
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Chromosomal rearrangement
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9HBE5 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| interleukin-21-mediated signaling pathway | ||
| natural killer cell activation | ||
| cytokine-mediated signaling pathway | ||
| immunoglobulin mediated immune response |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| membrane | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| cytokine receptor activity | ||
| interleukin-21 receptor activity | ||
| transmembrane signaling receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Interleukin-21 receptor
- Functional Category
-
- G: Carbohydrate transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| InterPro |
|---|
| Fibronectin type III superfamily |
| Fibronectin type III |
| Immunoglobulin-like fold |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050745 | diffuse large B-cell lymphoma | |
| DOID:0111982 | immunodeficiency 56 | |
| DOID:12177 | common variable immunodeficiency | |
| DOID:13241 | Behcet's disease | |
| DOID:13375 | temporal arteritis | |
| DOID:2377 | multiple sclerosis | |
| DOID:3310 | atopic dermatitis | |
| DOID:526 | human immunodeficiency virus infectious disease | |
| DOID:707 | B-cell lymphoma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 101872660 | MELUD19585 | |||
| 101943915 | CHRPI01642 | |||
| 101959908 | ICTTR12703 | |||
| 102007025 | CHILA19649 | |||
| 102135042 | MACFA24562 | |||
| 102176844 | CAPHI16932 | |||
| 103230109 | CHLSB14533 | |||
| 103258572 | CARSF20718 | |||
| 103281084 | ANOCA12396 | |||
| 103741072 | NANGA14598 |
