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glycoprotein VI platelet

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

51206

KEGG Gene ID

PubChem

51206

Alliance of Genome Resources

HGNC:14388

Annotation

Keyword

3D-structure
Alternative splicing
Blood coagulation
Cell membrane
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Immunoglobulin domain
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9HCN6	Glycoprotein 6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
collagen-activated tyrosine kinase receptor signaling pathway	IBA
collagen-activated signaling pathway	TAS
platelet aggregation	IEA
positive regulation of platelet aggregation	TAS

GO Hierarchy

biological process

cellular process [inference]

cell activation [inference]

platelet activation

cell adhesion [inference]

cell-cell adhesion [inference]

homotypic cell-cell adhesion [inference]

platelet aggregation

signal transduction [inference]

immune response-regulating signaling pathway

immune response-inhibiting signal transduction [inference]

immune response-inhibiting cell surface receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-inhibiting cell surface receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-inhibiting cell surface receptor signaling pathway

enzyme-linked receptor protein signaling pathway

cell surface receptor protein tyrosine kinase signaling pathway [inference]

collagen-activated tyrosine kinase receptor signaling pathway

collagen-activated signaling pathway

collagen-activated tyrosine kinase receptor signaling pathway

multicellular organismal process [inference]

cell activation [inference]

platelet activation

developmental process [inference]

anatomical structure development [inference]

system development [inference]

vasculature development

animal gross anatomical part developmental process [inference]

vasculature development

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of immune response [inference]

immune response-regulating signaling pathway

immune response-inhibiting signal transduction [inference]

immune response-inhibiting cell surface receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-inhibiting cell surface receptor signaling pathway

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion [inference]

positive regulation of platelet aggregation

regulation of response to stimulus [inference]

regulation of immune response [inference]

immune response-regulating signaling pathway

immune response-inhibiting signal transduction [inference]

immune response-inhibiting cell surface receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-inhibiting cell surface receptor signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway

immune response-inhibiting signal transduction [inference]

immune response-inhibiting cell surface receptor signaling pathway

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-inhibiting cell surface receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

immune response-inhibiting cell surface receptor signaling pathway

enzyme-linked receptor protein signaling pathway

cell surface receptor protein tyrosine kinase signaling pathway [inference]

collagen-activated tyrosine kinase receptor signaling pathway

collagen-activated signaling pathway

collagen-activated tyrosine kinase receptor signaling pathway

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion [inference]

positive regulation of platelet aggregation

regulation of homotypic cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion [inference]

positive regulation of platelet aggregation

regulation of platelet aggregation [inference]

positive regulation of platelet aggregation

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion [inference]

positive regulation of platelet aggregation

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of homotypic cell-cell adhesion [inference]

positive regulation of platelet aggregation

regulation of cell activation [inference]

regulation of platelet activation [inference]

regulation of platelet aggregation [inference]

positive regulation of platelet aggregation

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of platelet activation [inference]

regulation of platelet aggregation [inference]

positive regulation of platelet aggregation

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA
plasma membrane	IBA
plasma membrane	IEA
cell surface	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell surface

membrane [inference]

plasma membrane

membrane microdomain [inference]

membrane raft

external encapsulating structure [inference]

extracellular matrix

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

tetraspanin-enriched microdomain

Displaying entries **1 - 5** of 9 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
transmembrane signaling receptor activity	TAS
transmembrane signaling receptor activity	IBA
protein binding	IPI
collagen binding	TAS
collagen binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein tyrosine kinase binding

protein-containing complex binding [inference]

collagen binding

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity

collagen receptor activity

immune receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:2218	blood platelet disease	Alliance of Genome Resources
DOID:11847	coronary thrombosis	Alliance of Genome Resources
DOID:9352	type 2 diabetes mellitus	Alliance of Genome Resources
DOID:5844	myocardial infarction	Alliance of Genome Resources
DOID:9408	acute myocardial infarction	Alliance of Genome Resources
DOID:0111057	platelet-type bleeding disorder 11	Alliance of Genome Resources