GlyCosmos Portal

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
extrinsic component of synaptic vesicle membrane	IEA
intracellular membrane-bounded organelle	IDA
cytosol	IDA ISS TAS
clathrin-coated vesicle membrane	IEA
secretory granule	IDA	23035048

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

proton-transporting two-sector ATPase complex

proton-transporting V-type ATPase complex

proton-transporting two-sector ATPase complex, catalytic domain [inference]

proton-transporting V-type ATPase, V1 domain [inference]

vacuolar proton-transporting V-type ATPase, V1 domain

transmembrane transporter complex

catalytic complex [inference]

ATPase complex [inference]

proton-transporting two-sector ATPase complex

proton-transporting V-type ATPase complex

transporter complex [inference]

transmembrane transporter complex

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

coated vesicle membrane [inference]

clathrin-coated vesicle membrane

bounding membrane of organelle [inference]

Golgi membrane

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane

coated vesicle membrane [inference]

clathrin-coated vesicle membrane

plasma membrane region [inference]

apical plasma membrane

extrinsic component of membrane [inference]

extrinsic component of organelle membrane [inference]

extrinsic component of synaptic vesicle membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

microvillus

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
proton-transporting ATPase activity, rotational mechanism	IBA
proton-transporting ATP synthase activity, rotational mechanism	IEA
ATP binding	IEA
protein binding	IPI	23035048 33208464
ATP hydrolysis activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

ligase activity [inference]

proton-transporting ATP synthase activity, rotational mechanism

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

proton channel activity [inference]

proton-transporting ATP synthase activity, rotational mechanism

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

proton channel activity [inference]

proton-transporting ATP synthase activity, rotational mechanism

proton transmembrane transporter activity [inference]

proton channel activity [inference]

proton-transporting ATP synthase activity, rotational mechanism

proton-transporting ATPase activity, rotational mechanism

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

proton channel activity [inference]

proton-transporting ATP synthase activity, rotational mechanism

proton-transporting ATPase activity, rotational mechanism

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

proton channel activity [inference]

proton-transporting ATP synthase activity, rotational mechanism

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

ATPase-coupled ion transmembrane transporter activity [inference]

ATPase activity, coupled to transmembrane movement of ions, rotational mechanism [inference]

proton-transporting ATPase activity, rotational mechanism

active monoatomic ion transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled monoatomic cation transmembrane transporter activity [inference]

proton-transporting ATPase activity, rotational mechanism

ATPase-coupled ion transmembrane transporter activity [inference]

ATPase activity, coupled to transmembrane movement of ions, rotational mechanism [inference]

proton-transporting ATPase activity, rotational mechanism

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000114573

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K02145

Name

V-type H+-transporting ATPase subunit A [EC:7.1.2.2]

References

Rhea

RHEA:57720

H₂O + H⁺ + ATP

H⁺ + phosphate + ADP

Enzyme

7.1.2.2

PMID

Disease

Disease Ontology

Displaying entries **81 - 90** of **111** in total

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DO ID	Disease Name	Source
DOID:3144	cutis laxa	DisGeNET
DOID:3535	Unverricht-Lundborg syndrome	DisGeNET
DOID:3891	placental insufficiency	DisGeNET
DOID:4028	angioma serpiginosum	DisGeNET
DOID:4480	achondroplasia	DisGeNET
DOID:4626	hydranencephaly	DisGeNET
DOID:483	cavernous hemangioma	DisGeNET
DOID:529	blepharospasm	DisGeNET
DOID:539	ophthalmoplegia	DisGeNET
DOID:540	strabismus	DisGeNET

The Human Phenotype Ontology

Displaying entries **1 - 10** of **143** in total

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HPO ID	HPO Term
HP:0000006	Autosomal dominant inheritance
HP:0000007	Autosomal recessive inheritance
HP:0000023	Inguinal hernia
HP:0000054	Micropenis
HP:0000218	High palate
HP:0000252	Microcephaly
HP:0000253	Progressive microcephaly
HP:0000272	Malar flattening
HP:0000278	Retrognathia
HP:0000298	Mask-like facies

Displaying **all 4** entries
Disease ID	Disease Name
OMIM:618012	epileptic encephalopathy, infantile or early childhood, 3
ORPHA:357074	autosomal recessive cutis laxa type 2, classic type
ORPHA:442835	developmental and epileptic encephalopathy, 58 developmental delay and seizures with or without movement abnormalities intellectual disability, X-linked, syndromic, Houge type intellectual disability, autosomal dominant 55, with seizures intellectual disability, autosomal dominant 56 undetermined early-onset epileptic encephalopathy
OMIM:617403	autosomal recessive cutis laxa type 2D

PubChem Disease

MedGen Diseases

OMIM Phenotypes

KEGG Diseases

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **91 - 100** of **142** in total

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Species	Gene ID	Orthologous MAtrix
Oryzias melastigma	112151199	ORYME19989
Takifugu rubripes	101062023	TAKRU02456
Takifugu rubripes	101072050	TAKRU13454
Neolamprologus brichardi	102781495	NEOBR22394
Chinchilla lanigera	102005949	CHILA08381
Kryptolebias marmoratus	108230230	KRYMA03693
Kryptolebias marmoratus	108236878	KRYMA11645
Aotus nancymaae	105724990	AOTNA19635
Phascolarctos cinereus	110222274	PHACI00680
Saimiri boliviensis boliviensis	101041261	SAIBB25237

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

PubChem Disease

International Collaboration

Acknowledgements