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torsin family 2 member A

Summary

Gene Symbol

TOR2A

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 534311
PubChem: 534311

Annotation

Keyword

ATP-binding
Alternative splicing
Cleavage on pair of basic residues
Endoplasmic reticulum
Glycoprotein
Hormone
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A4FUH1	Torsin family 2 member A
P0C7W1	Torsin family 2 member A Torsin-2A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
chaperone cofactor-dependent protein refolding	IEA	22301074

GO Hierarchy

biological process

cellular process [inference]

protein folding [inference]

'de novo' protein folding [inference]

'de novo' post-translational protein folding [inference]

chaperone cofactor-dependent protein refolding

chaperone-mediated protein folding [inference]

chaperone cofactor-dependent protein refolding

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum lumen	IEA	30032202
extracellular region
endoplasmic reticulum	IEA	22301074
nuclear envelope	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

envelope [inference]

organelle envelope [inference]

nuclear envelope

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ATP hydrolysis activity	IEA	22301074 30032202
hormone activity
ATP binding	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor ligand activity [inference]

hormone activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Torsin

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
ATP binding

Displaying **all 3** entries
InterPro
P-loop containing nucleoside triphosphate hydrolase
Torsin-1A, C-terminal domain
Torsin

Ortholog

Displaying entries **41 - 50** of 90 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Physeter catodon	102992999	9755_0:001b17
Astyanax mexicanus	103040138			ASTMX14582
Chlorocebus sabaeus	103239834			CHLSB03023
Nannospalax galili	103727273			NANGA03903
Rhinopithecus roxellana	104665879			RHIRO31745
Bison bison bison	105000848	43346_0:003bc7
Camelus bactrianus	105065959	9837_0:0015d8
Camelus dromedarius	105092601	9838_0:000a5b
Pteropus vampyrus	105294838			PTEVA14341
Macaca nemestrina	105463951			MACNE28289

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024