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torsin family 2 member A

Summary

Gene Symbol

TOR2A

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 534311
PubChem: 534311

Annotation

Keyword

ATP-binding
Alternative splicing
Cleavage on pair of basic residues
Endoplasmic reticulum
Glycoprotein
Hormone
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A4FUH1	Torsin family 2 member A
P0C7W1	Torsin family 2 member A Torsin-2A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
chaperone cofactor-dependent protein refolding	IEA	22301074

GO Hierarchy

biological process

cellular process [inference]

protein folding [inference]

'de novo' protein folding [inference]

'de novo' post-translational protein folding [inference]

chaperone cofactor-dependent protein refolding

chaperone-mediated protein folding [inference]

chaperone cofactor-dependent protein refolding

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum lumen	IEA	30032202
extracellular region
endoplasmic reticulum	IEA	22301074
nuclear envelope	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

envelope [inference]

organelle envelope [inference]

nuclear envelope

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ATP hydrolysis activity	IEA	22301074 30032202
hormone activity
ATP binding	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor ligand activity [inference]

hormone activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Torsin

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
ATP binding

Displaying **all 3** entries
InterPro
P-loop containing nucleoside triphosphate hydrolase
Torsin-1A, C-terminal domain
Torsin

Ortholog

Displaying entries **51 - 60** of 90 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mandrillus leucophaeus	105545374			MANLE21266
Cercocebus atys	105576256			CERAT27614
Aotus nancymaae	105721175			AOTNA09722
Propithecus coquereli	105806635			PROCO11374
Microcebus murinus	105875222			MICMU09015
Dipodomys ordii	105989441			DIPOR14796
Sinocyclocheilus grahami	107552620			SINGR74245
Sinocyclocheilus grahami	107587655			SINGR23672
Ictalurus punctatus	108256045			ICTPU17342
Rhinopithecus bieti	108542722			RHIBE31243

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024