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MIRAGE
beta-secretase 2
Summary
- Gene Symbol
-
- BACE2
- Organism
- Bos taurus (domestic cattle)
Annotation
- Keyword
-
- Disulfide bond
- Glycoprotein
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| E1BKV4 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis |
|
|
| membrane protein ectodomain proteolysis | ||
| amyloid-beta metabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| endosome | ||
| trans-Golgi network | ||
| plasma membrane | ||
| membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| aspartic-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Beta-secretase
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| amyloid-beta metabolic process |
| aspartic-type endopeptidase activity |
| hydrolase activity |
| membrane protein ectodomain proteolysis |
| proteolysis |
| InterPro |
|---|
| Aspartic peptidase A1 family |
| Aspartic peptidase domain superfamily |
| Aspartic peptidase, active site |
| Beta-secretase BACE |
| Memapsin-like |
| Peptidase family A1 domain |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 25825 | HUMAN58690 | ||
| 56175 | MOUSE18582 | ||
| 288227 | RATNO03994 | ||
| 449818 | DANRE08623 | ||
| 747819 | PANTR25710 | ||
| 100016587 | MONDO21518 | ||
| 100080196 | ORNAN10120 | ||
| 100080224 | ORNAN10120 | ||
| 100080247 | ORNAN10120 | ||
| 100224177 | TAEGU10265 |
