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cholinergic receptor, muscarinic 5

Summary

Gene Symbol

Chrm5

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

53949

PubChem

53949

Alliance of Genome Resources

RGD:620027

Annotation

Keyword

Cell membrane
Direct protein sequencing
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Postsynaptic cell membrane
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P08911
A6HP54

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
gastric acid secretion	IEA
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	IBA
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway	IBA
chemical synaptic transmission	IBA
dopamine transport	ISO

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

G protein-coupled acetylcholine receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway [inference]

G protein-coupled acetylcholine receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

multicellular organismal process [inference]

system process [inference]

digestive system process [inference]

gastric acid secretion

nervous system process [inference]

transmission of nerve impulse

localization [inference]

establishment of localization [inference]

transport [inference]

secretion [inference]

acid secretion [inference]

gastric acid secretion

organic substance transport [inference]

monoamine transport [inference]

catecholamine transport [inference]

dopamine transport

organic hydroxy compound transport [inference]

catecholamine transport [inference]

dopamine transport

nitrogen compound transport [inference]

monoamine transport [inference]

catecholamine transport [inference]

dopamine transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation [inference]

regulation of phosphatidylinositol dephosphorylation

regulation of phospholipid metabolic process [inference]

regulation of phosphatidylinositol dephosphorylation

regulation of macromolecule metabolic process [inference]

regulation of phosphatidylinositol dephosphorylation

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of phospholipid metabolic process [inference]

regulation of phosphatidylinositol dephosphorylation

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

G protein-coupled acetylcholine receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway [inference]

G protein-coupled acetylcholine receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

regulation of cellular metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of phosphate metabolic process [inference]

regulation of dephosphorylation [inference]

regulation of phosphatidylinositol dephosphorylation

regulation of phospholipid metabolic process [inference]

regulation of phosphatidylinositol dephosphorylation

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA
dendrite	IBA
synapse	IBA
postsynaptic membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

Displaying **all 3** entries
GO Term	Evidence Code	PMID
G protein-coupled serotonin receptor activity
G protein-coupled acetylcholine receptor activity	IDA	2540186
G protein-coupled acetylcholine receptor activity	IBA

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled amine receptor activity [inference]

G protein-coupled neurotransmitter receptor activity [inference]

G protein-coupled acetylcholine receptor activity

acetylcholine receptor activity [inference]

G protein-coupled acetylcholine receptor activity

neurotransmitter receptor activity [inference]

postsynaptic neurotransmitter receptor activity [inference]

acetylcholine receptor activity [inference]

G protein-coupled acetylcholine receptor activity

G protein-coupled neurotransmitter receptor activity [inference]

G protein-coupled acetylcholine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

muscarinic acetylcholine receptor

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
G protein-coupled acetylcholine receptor signaling pathway
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

Displaying **all 3** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Muscarinic acetylcholine receptor family

Ortholog

Displaying entries **41 - 50** of 94 in total

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Species	Gene ID	Orthologous MAtrix
Tursiops truncatus	101317598	TURTR15861
Octodon degus	101562268	OCTDE21370
Jaculus jaculus	101599428	JACJA21648
Mustela putorius furo	101679448	MUSPF14061
Anas platyrhynchos platyrhynchos	101805433	ANAPP17453
Ficedula albicollis	101819745	FICAL02888
Melopsittacus undulatus	101877836	MELUD07757
Chrysemys picta bellii	101938589	CHRPI35169
Ictidomys tridecemlineatus	101957945	ICTTR07361
Chinchilla lanigera	102022696	CHILA05117