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MIRAGE
toll like receptor 9
Summary
- Gene Symbol
-
- TLR9
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cytoplasmic vesicle
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Golgi apparatus
- Inflammatory response
- Innate immunity
- Leucine-rich repeat
- Lysosome
- Palmitate
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9NR96 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| microglial cell activation | ||
| toll-like receptor signaling pathway | ||
| toll-like receptor signaling pathway | ||
| positive regulation of immunoglobulin production | ||
| regulation of dendritic cell cytokine production |
GO Hierarchy
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of intestinal epithelial cell development
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of chemokine production
- positive regulation of granulocyte macrophage colony-stimulating factor production
- positive regulation of type II interferon production
- positive regulation of interleukin-10 production
- positive regulation of interleukin-12 production
- positive regulation of interleukin-18 production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-8 production
- positive regulation of intestinal epithelial cell development
biological process
immune system process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of transport [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of transmembrane transport [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cell communication [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| interleukin-1 receptor binding | ||
| siRNA binding | ||
| pattern recognition receptor activity | ||
| pattern recognition receptor activity | ||
| protein homodimerization activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Leucine-rich repeat
- Functional Category
-
- K: Transcription
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| InterPro |
|---|
| Leucine-rich repeat domain superfamily |
| Leucine-rich repeat, typical subtype |
| Leucine-rich repeat-containing N-terminal, plant-type |
| Leucine-rich repeat |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080162 | lupus nephritis | |
| DOID:10533 | viral pneumonia | |
| DOID:1287 | cardiovascular system disease | |
| DOID:13166 | allergic bronchopulmonary aspergillosis | |
| DOID:1485 | cystic fibrosis | |
| DOID:1883 | hepatitis C | |
| DOID:2043 | hepatitis B | |
| DOID:2799 | bronchiolitis obliterans | |
| DOID:2841 | asthma | |
| DOID:2957 | pulmonary tuberculosis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 43690 | RGD:631352 | ||
| 54106 | Xenbase:XB-GENE-865657 | ||
| 81897 | ZFIN:ZDB-GENE-040219-10 | MOUSE60630 | |
| 174079 | ZFIN:ZDB-GENE-040219-10 | ||
| 282602 | BOVIN17719 | ||
| 338457 | RATNO40494 | ||
| 397007 | PIGXX04207 | ||
| 403502 | CANLF07441 | ||
| 470827 | PANTR31285 | ||
| 493839 | FELCA03744 |
