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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Toll-like receptor 9
Summary
- UniProt ID
- Q9NR96
- Gene Symbol
-
- TLR9
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- Q9NR96
- PubChem
- Q9NR96
- The Human Metabolome Database
- HMDBP02761
- The O-GlcNAc Database
- Q9NR96
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cytoplasmic vesicle
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Golgi apparatus
- Inflammatory response
- Innate immunity
- Leucine-rich repeat
- Lysosome
- Palmitate
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| basolateral plasma membrane |
| apical plasma membrane |
| early phagosome |
| endosome |
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| Golgi membrane |
| extracellular region |
| cytoplasm |
| lysosome |
| GO Term |
|---|
| interleukin-1 receptor binding |
| siRNA binding |
| pattern recognition receptor activity |
| protein homodimerization activity |
| unmethylated CpG binding |
Sequence
MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 64 | N-linked (GlcNAc...) asparagine | |||
| 129 | N-linked (GlcNAc...) asparagine |
|
||
| 200 | N-linked (GlcNAc...) asparagine |
|
||
| 209 |
|
|
||
| 210 | N-linked (GlcNAc...) asparagine | |||
| 242 | N-linked (GlcNAc...) asparagine | |||
| 300 | N-linked (GlcNAc...) asparagine |
|
||
| 340 | N-linked (GlcNAc...) asparagine |
|
||
| 469 | N-linked (GlcNAc...) asparagine |
|
||
| 474 | N-linked (GlcNAc...) asparagine |
|
G80920RR
G62765YT
G31852PQ
G83460ZZ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| MyD88 dependent cascade initiated on endosome | Homo sapiens |
| PI3K Cascade | Homo sapiens |
| Potential therapeutics for SARS | Homo sapiens |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | Homo sapiens |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | Homo sapiens |
| Toll Like Receptor 9 (TLR9) Cascade | Homo sapiens |
| Trafficking and processing of endosomal TLR | Homo sapiens |
