proopiomelanocortin
| UniProt | Protein Name |
|---|---|
| P01189 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| generation of precursor metabolites and energy | ||
| signal transduction | ||
| neuropeptide signaling pathway | ||
| cell-cell signaling | ||
| regulation of blood pressure |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| extracellular space | ||
| cytoplasm | ||
| peroxisome |
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled receptor binding | ||
| G protein-coupled receptor binding | ||
| signaling receptor binding | ||
| hormone activity | ||
| hormone activity |
| Gene Ontology |
|---|
| G protein-coupled receptor binding |
| hormone activity |
| neuropeptide hormone activity |
| neuropeptide signaling pathway |
| regulation of corticosterone secretion |
| InterPro |
|---|
| Opiodes neuropeptide |
| Pro-opiomelanocortin N-terminal |
| Pro-opiomelanocortin/corticotropin, ACTH, central region |
| Pro-opiomelanocortin |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050696 | fetal alcohol spectrum disorder | |
| DOID:0050741 | alcohol dependence | |
| DOID:0050742 | nicotine dependence | |
| DOID:2987 | familial Mediterranean fever | |
| DOID:8398 | osteoarthritis | |
| DOID:9970 | obesity |
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 5443 | Xenbase:XB-GENE-483703 | ||
| 18976 | Xenbase:XB-GENE-483703 | MOUSE09547 | |
| 24664 | RATNO36044 | ||
| 281416 | BOVIN02862 | ||
| 353221 | DANRE12058 | ||
| 373802 | Xenbase:XB-GENE-483703 | ||
| 380532 | Xenbase:XB-GENE-483703 | ||
| 403659 | CANLF04943 | ||
| 443212 | SHEEP13586 | ||
| 459074 | PANTR27181 |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: August 4, 2025