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Standards Ontologies Notations
Guidelines
MIRAGE
ATR serine/threonine kinase

Summary
Gene Symbol
  • ATR
Organism
Homo sapiens (human)
NCBI Gene
545
PubChem
545
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Alternative splicing
  • Chromosome
  • DNA repair
  • DNA-binding
  • Disease variant
  • Dwarfism
  • Intellectual disability
  • Manganese
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Serine/threonine-protein kinase
Proteins
Displaying 1 entry
UniProt Protein Name
Q13535
  • Ataxia telangiectasia and Rad3-related protein
  • FRAP-related protein 1
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 33 in total
GO Term Evidence Code PMID
DNA damage checkpoint signaling
DNA damage checkpoint signaling
telomere maintenance
nucleobase-containing compound metabolic process
DNA replication
GO Hierarchy
Displaying entries 1 - 5 of 30 in total
GO Term Evidence Code PMID
DNA binding
protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine kinase activity
protein serine/threonine kinase activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
protein kinase
Functional Category
  • I: Lipid transport and metabolism
  • Q: Secondary metabolites biosynthesis, transport and catabolism
  • T: Signal transduction mechanisms
Displaying all 7 entries
Gene Ontology
ATP binding
TOR signaling
kinase activity
negative regulation of macroautophagy
nucleotide binding
phosphorylation
transferase activity
Displaying entries 1 - 10 of 13 in total
InterPro
Armadillo-like helical
Armadillo-type fold
FATC domain
FKBP12-rapamycin binding domain superfamily
FKBP12-rapamycin binding domain
PIK-related kinase, FAT
PIK-related kinase
Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily
Phosphatidylinositol 3-/4-kinase, catalytic domain
Phosphatidylinositol 3/4-kinase, conserved site
Disease
Disease Ontology
Displaying all 5 entries
DO ID Disease Name Source
DOID:0070007 Seckel syndrome 1
DOID:0080202 adenoid cystic carcinoma
DOID:1324 lung cancer
DOID:1793 pancreatic cancer
DOID:219 colon cancer
Ortholog
Displaying entries 31 - 40 of 80 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
101670820 MUSPF12631
101701996 HETGA18107
101880813 MELUD10417
101926636 MACFA26212
101945312 CHRPI15994
102013741 CHILA21160
102178489 CAPHI12511
102354343 LATCH08724
102440870 MYOLU03144
102459396 PELSI18159
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025