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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

tRNA isopentenyltransferase 1

Summary

Gene Symbol

TRIT1

Organism

Homo sapiens (human)

External Links

NCBI Gene

54802

PubChem

54802

Alliance of Genome Resources

HGNC:20286

Annotation

Keyword

ATP-binding
Alternative splicing
Cytoplasm
Disease variant
Mitochondrion
Phosphoprotein
Primary mitochondrial disease
Reference proteome
Transferase
Transit peptide
Zinc-finger
tRNA processing

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q3T7C7
Q53F11
Q9H3H1	Isopentenyl-diphosphate:tRNA isopentenyltransferase hGRO1 tRNA isopentenyltransferase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
tRNA modification	IDA	24126054
tRNA modification	IBA
mitochondrial tRNA modification	TAS
mitochondrial tRNA modification	IDA	24901367 34774131

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

RNA processing [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

RNA modification [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

tRNA threonylcarbamoyladenosine metabolic process [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

mitochondrial gene expression [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

mitochondrial gene expression [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

RNA processing [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

RNA modification [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

tRNA threonylcarbamoyladenosine metabolic process [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

RNA processing [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

RNA modification [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

tRNA threonylcarbamoyladenosine metabolic process [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

mitochondrial gene expression [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

RNA processing [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

RNA modification [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

tRNA threonylcarbamoyladenosine metabolic process [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

RNA processing [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

RNA modification [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

tRNA threonylcarbamoyladenosine metabolic process [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

mitochondrial gene expression [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

macromolecule modification [inference]

RNA modification [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

RNA processing [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

RNA modification [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

tRNA threonylcarbamoyladenosine metabolic process [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

RNA processing [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

RNA modification [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

tRNA threonylcarbamoyladenosine metabolic process [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

mitochondrial gene expression [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

RNA processing [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

RNA modification [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

tRNA threonylcarbamoyladenosine metabolic process [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

RNA processing [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

RNA modification [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

tRNA threonylcarbamoyladenosine metabolic process [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

mitochondrial gene expression [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mitochondrial RNA metabolic process [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

RNA processing [inference]

mitochondrial RNA processing [inference]

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

RNA modification [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial RNA modification [inference]

mitochondrial tRNA modification

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

tRNA threonylcarbamoyladenosine metabolic process [inference]

mitochondrial tRNA modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification

mitochondrial tRNA modification

mitochondrial tRNA processing [inference]

mitochondrial tRNA modification

Displaying **all 4** entries
GO Term	Evidence Code	PMID
mitochondrion	IDA	24901367
mitochondrion	IBA
mitochondrion	HTP	34800366
mitochondrial matrix	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
nucleic acid binding	IEA
protein binding	IPI	32814053
ATP binding	IEA
zinc ion binding	IEA
tRNA dimethylallyltransferase activity	EXP	24901367

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring alkyl or aryl (other than methyl) groups [inference]

tRNA dimethylallyltransferase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

catalytic activity, acting on a tRNA [inference]

tRNA dimethylallyltransferase activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleic acid binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

trna dimethylallyltransferase

Functional Category

J: Translation, ribosomal structure and biogenesis
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 5** entries
Gene Ontology
AMP dimethylallyltransferase activity
ATP binding
nucleotide binding
tRNA processing
transferase activity

Displaying **all 3** entries
InterPro
Dimethylallyltransferase
IPP transferase
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111464	combined oxidative phosphorylation deficiency 35	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 57 in total

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5

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	54802	Xenbase:XB-GENE-494505
Mus musculus	66966		MOUSE41800
Rattus norvegicus	362586		RATNO34651
Pan troglodytes	456785		PANTR20744
Canis lupus familiaris	475320		CANLF03916
Bos taurus	535006		BOVIN27233
Danio rerio	553523		DANRE15634
Macaca mulatta	716422		MACMU22060
Equus caballus	100068446		HORSE28238
Taeniopygia guttata	100225653		TAEGU13505

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Acknowledgements

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025