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solute carrier family 66 member 1

Summary

Gene Symbol

SLC66A1

Organism

Homo sapiens (human)

External Links

NCBI Gene

54896

PubChem

54896

Alliance of Genome Resources

HGNC:26001

Annotation

Keyword

Alternative splicing
Amino-acid transport
Glycoprotein
Lysosome
Reference proteome
Repeat
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q6ZP29	PQ-loop repeat-containing protein 2 Solute carrier family 66 member 1
A0A024RAA1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
lysine transport	IDA	22822152
L-arginine transmembrane transport	IDA	22822152 34344826
intracellular amino acid homeostasis	IDA	22822152
transmembrane transport	TAS
L-histidine transmembrane transport	IDA	34344826

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

azole transmembrane transport [inference]

L-histidine transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular amino acid homeostasis

chemical homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular amino acid homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

transmembrane transport

azole transmembrane transport [inference]

L-histidine transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

aromatic amino acid transport [inference]

L-histidine transmembrane transport

basic amino acid transport [inference]

lysine transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

aromatic amino acid transport [inference]

L-histidine transmembrane transport

basic amino acid transport [inference]

lysine transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

azole transmembrane transport [inference]

L-histidine transmembrane transport

modified amino acid transport [inference]

L-arginine transmembrane transport

nitrogen compound transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

aromatic amino acid transport [inference]

L-histidine transmembrane transport

basic amino acid transport [inference]

lysine transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

azole transmembrane transport [inference]

L-histidine transmembrane transport

modified amino acid transport [inference]

L-arginine transmembrane transport

Displaying **all 3** entries
GO Term	Evidence Code	PMID
intracellular membrane-bounded organelle	IDA
organelle membrane	IDA	22822152
lysosomal membrane	IBA IDA TAS	22822152 34344826

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32296183
L-arginine transmembrane transporter activity	IDA	22822152 34344826
L-lysine transmembrane transporter activity	IBA IDA	22822152 34344826
L-histidine transmembrane transporter activity	IDA	34344826
basic amino acid transmembrane transporter activity	ISS TAS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

aromatic amino acid transmembrane transporter activity [inference]

L-histidine transmembrane transporter activity

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

aromatic amino acid transmembrane transporter activity [inference]

L-histidine transmembrane transporter activity

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

modified amino acid transmembrane transporter activity [inference]

L-arginine transmembrane transporter activity

azole transmembrane transporter activity [inference]

L-histidine transmembrane transporter activity

salt transmembrane transporter activity [inference]

L-lysine transmembrane transporter activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

pq loop repeat

Functional Category

K: Transcription
T: Signal transduction mechanisms

Displaying 1 entry
InterPro
PQ-loop repeat

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3211	lysosomal storage disease	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 76 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Loxodonta africana	100673785		LOXAF11310
Oreochromis niloticus	100706031		ORENI39019
Cavia porcellus	100723829		CAVPO11990
Cricetulus griseus	100752042		CRIGR16008
Otolemur garnettii	100959081		OTOGA16896
Pan paniscus	100980960	9597_0:0006df	PANPA00468
Papio anubis	101010887		PAPAN20618
Saimiri boliviensis boliviensis	101037288		SAIBB24504
Ovis aries	101109152		SHEEP10080
Gorilla gorilla gorilla	101141555	9595_0:000664	GORGO20308