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solute carrier family 66 member 1

Summary

Gene Symbol

SLC66A1

Organism

Homo sapiens (human)

External Links

NCBI Gene

54896

PubChem

54896

Alliance of Genome Resources

HGNC:26001

Annotation

Keyword

Alternative splicing
Amino-acid transport
Glycoprotein
Lysosome
Reference proteome
Repeat
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q6ZP29	PQ-loop repeat-containing protein 2 Solute carrier family 66 member 1
A0A024RAA1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
lysine transport	IDA	22822152
L-arginine transmembrane transport	IDA	22822152 34344826
intracellular amino acid homeostasis	IDA	22822152
transmembrane transport	TAS
L-histidine transmembrane transport	IDA	34344826

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

azole transmembrane transport [inference]

L-histidine transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular amino acid homeostasis

chemical homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular amino acid homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

transmembrane transport

azole transmembrane transport [inference]

L-histidine transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

aromatic amino acid transport [inference]

L-histidine transmembrane transport

basic amino acid transport [inference]

lysine transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

aromatic amino acid transport [inference]

L-histidine transmembrane transport

basic amino acid transport [inference]

lysine transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

azole transmembrane transport [inference]

L-histidine transmembrane transport

modified amino acid transport [inference]

L-arginine transmembrane transport

nitrogen compound transport [inference]

amino acid transport [inference]

amino acid transmembrane transport [inference]

L-alpha-amino acid transmembrane transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

aromatic amino acid transport [inference]

L-histidine transmembrane transport

basic amino acid transport [inference]

lysine transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport [inference]

L-lysine transport [inference]

L-alpha-amino acid transmembrane transport [inference]

azole transmembrane transport [inference]

L-histidine transmembrane transport

modified amino acid transport [inference]

L-arginine transmembrane transport

Displaying **all 3** entries
GO Term	Evidence Code	PMID
intracellular membrane-bounded organelle	IDA
organelle membrane	IDA	22822152
lysosomal membrane	IBA IDA TAS	22822152 34344826

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32296183
L-arginine transmembrane transporter activity	IDA	22822152 34344826
L-lysine transmembrane transporter activity	IBA IDA	22822152 34344826
L-histidine transmembrane transporter activity	IDA	34344826
basic amino acid transmembrane transporter activity	ISS TAS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

aromatic amino acid transmembrane transporter activity [inference]

L-histidine transmembrane transporter activity

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity [inference]

aromatic amino acid transmembrane transporter activity [inference]

L-histidine transmembrane transporter activity

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity [inference]

modified amino acid transmembrane transporter activity [inference]

L-arginine transmembrane transporter activity

azole transmembrane transporter activity [inference]

L-histidine transmembrane transporter activity

salt transmembrane transporter activity [inference]

L-lysine transmembrane transporter activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

pq loop repeat

Functional Category

K: Transcription
T: Signal transduction mechanisms

Displaying 1 entry
InterPro
PQ-loop repeat

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3211	lysosomal storage disease	Alliance of Genome Resources

Ortholog

Displaying entries **41 - 50** of 76 in total

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Species	Gene ID	Orthologous MAtrix
Callorhinchus milii	103187650	CALMI37215
Chlorocebus sabaeus	103225479	CHLSB09305
Carlito syrichta	103276176	CARSF16194
Nannospalax galili	103724713	NANGA18110
Serinus canaria	103824348	SERCA21898
Rhinopithecus roxellana	104679829	RHIRO19304
Esox lucius	105026941	ESOLU35680
Macaca nemestrina	105483113	MACNE33881
Mandrillus leucophaeus	105548897	MANLE29246
Cercocebus atys	105595068	CERAT06502