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otolin 1a

Summary

Gene Symbol

otol1a

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

553759

PubChem

553759

Alliance of Genome Resources

ZFIN:ZDB-GENE-050707-1

Annotation

Keyword

Calcium
Collagen
Disulfide bond
Extracellular matrix
Glycoprotein
Metal-binding
Reference proteome
Repeat
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
A5PN28	zOtolin1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
extracellular matrix organization	IBA
biomineral tissue development	IDA	36791829
otolith mineralization	IDA	29076638
otolith development	IMP	15905077
protein complex oligomerization	IDA	35447266

GO Hierarchy

biological process

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization

extracellular structure organization [inference]

extracellular matrix organization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization

external encapsulating structure organization [inference]

extracellular matrix organization

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

biomineral tissue development

otolith mineralization

otolith development

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
collagen trimer	IEA
extracellular space	IBA
collagen-containing extracellular matrix	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

collagen trimer

cellular anatomical entity [inference]

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

Displaying **all 3** entries
GO Term	Evidence Code	PMID
calcium ion binding	IDA	29076638
extracellular matrix structural constituent conferring tensile strength	IBA
metal ion binding	IEA

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent [inference]

extracellular matrix structural constituent conferring tensile strength

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Otolin-1-A

Functional Category

K: Transcription
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
C1q domain
Collagen triple helix repeat
Tumour necrosis factor-like domain superfamily

Ortholog

Displaying entries **1 - 10** of 76 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	1292	WB:WBGene00000653
Caenorhabditis elegans	1297	WB:WBGene00000603
Caenorhabditis elegans	1298	WB:WBGene00000752
Caenorhabditis elegans	8685	WB:WBGene00000754
Caenorhabditis elegans	50509	WB:WBGene00000754
Caenorhabditis elegans	81578	WB:WBGene00000613
Homo sapiens	131149	Xenbase:XB-GENE-950285	HUMAN73256
Mus musculus	229389	Xenbase:XB-GENE-950285	MOUSE36512
Rattus norvegicus	295117		RATNO24038
Caenorhabditis elegans	338872	WB:WBGene00001065