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MIRAGE
arginine vasopressin receptor 2
Summary
- Gene Symbol
-
- AVPR2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Diabetes insipidus
- Disease variant
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Palmitate
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P30518 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of systemic arterial blood pressure by vasopressin | ||
| positive regulation of systemic arterial blood pressure | ||
| renal water retention | ||
| G protein-coupled receptor signaling pathway | ||
| adenylate cyclase-modulating G protein-coupled receptor signaling pathway |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| endosome | ||
| endoplasmic reticulum | ||
| Golgi apparatus | ||
| plasma membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| vasopressin receptor activity | ||
| vasopressin receptor activity | ||
| vasopressin receptor activity | ||
| protein binding | ||
| peptide binding |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Gonadotropin-releasing hormone receptor
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cellular response to hormone stimulus |
| peptide binding |
| positive regulation of vasoconstriction |
| regulation of systemic arterial blood pressure by vasopressin |
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
| Vasopressin receptor |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081060 | X-linked nephrogenic diabetes insipidus | |
| DOID:0112121 | nephrogenic syndrome of inappropriate antidiuresis | |
| DOID:12387 | nephrogenic diabetes insipidus |
